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Table 2 Baseline characteristics according to PNI.

From: The association between malnutrition status and hemorrhagic transformation in patients with acute ischemic stroke receiving intravenous thrombolysis

 

low PNI ≤ 42.3

(n = 116)

high PNI > 42.3

(n = 692)

p-value

Male, n (%)

68 (58.6)

445 (64.3)

0.25

NIHSS (IQR)

10 (6–16)

7 (5–12)

< 0.001

BMI, kg/m2 (SD)

23.4 (21.4–24.8)

23.9 (21.8–25.7)

0.04

SVO

6 (5.2)

115 (16.6)

 

LAA

41 (35.3)

200 (28.9)

 

CE

38 (32.8)

205 (29.6)

 

UD

28 (24.1)

152 (22.0)

 

OD

3 (2.8)

20 (2.9)

 

Interval from arrival to IVT, min (IQR)

42 (35–56)

39 (29–54)

0.09

Previous stroke, n (%)

23 (19.8)

116 (16.8)

0.43

HTN, n (%)

68 (58.6)

412 (59.5)

0.92

CAD, n (%)

14 (12.1)

61 (8.8)

0.30

Current smoking, n (%)

22 (19.0)

151 (21.8)

0.54

Atrial fibrillation, n (%)

44 (37.9)

200 (28.9)

0.06

Previous use of antithrombotics, n (%)

25 (21.6)

195 (28.2)

0.15

tPA dose, n (%)

  

0.06

0.6 mg/kg

7 (6.0)

87 (12.6)

 

0.9 mg/kg

109 (94.0)

605 (87.4)

 

Total cholesterol, mg/dL (SD)

151.0 (44.9)

173.1 (42.3)

0.21

Albumin, mg/dL (SD)

3.0 (0.7)

4.2 (0.4)

< 0.001

Hemoglobin, g/dL (SD)

13.5 (2.0)

13.8 (2.0)

0.16

Creatinine, mg/dL (SD)

1.16 (0.88)

0.97 (0.46)

0.002

Platelet, x1000/µL (SD)

222.3 (73.1)

229.1 (70.1)

0.32

LDL, mg/dL (SD)

103.5 (38.4)

106.2 (33.7)

0.03

HbA1c, % (SD)

6.0 (2.0)

6.1 (1.1)

0.27

Prothrombin time, INR (SD)

1.04 (0.16)

1.02 (0.12)

0.35

CRP, mg/dL (SD)

11.3 (27.8)

7.0 (14.4)

0.001

Initial random glucose, mg/dL (SD)

151.5 (80.9)

142.7 (52.6)

0.004

SBP, mmHg (SD)

153.3 (24.7)

152.9 (27.7)

0.16

  1. Abbreviation: PNI, prognostic nutritional index; SD, standard deviation; NIHSS, National Institute Health of Stroke Scale; BMI, body mass index; IQR, interquartile range; SVO, small vessel occlusion; LAA, large artery atherosclerosis; CE, cardioembolism; UD, undetermined; OD, other determined; IVT, intravenous thrombolysis; HTN, hypertension; DM, diabetes mellitus; HL, hyperlipidemia; CAD, coronary artery disease; tPA, tissue plasminogen activator; LDL, low density lipoprotein; HbA1c, glycated hemoglobin; INR, international normalized ratio; CRP, C reactive protein; SBP, systolic blood pressure;