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Table 4 Multivariate analysis showing association between PNI system and outcomes

From: The association between malnutrition status and hemorrhagic transformation in patients with acute ischemic stroke receiving intravenous thrombolysis

 

END-SHT

 

Any HT

 

END-prog

 

3-month mRS 3–6

 
 

OR

95% CI

p-value

OR

95% CI

p-value

OR

95% CI

p-value

OR

95% CI

p-value

Low PNI

4.98

1.76–14.09

0.003

3.48

1.50–9.09

0.004

3.52

1.02–12.19

0.047

2.95

1.35–6.46

0.01

Age

0.995

0.97–1.03

0.92

0.999

0.98–1.02

0.96

1.03

0.99–1.06

0.11

1.05

1.03–1.06

< 0.001

Male

1.14

0.57–2.29

0.72

1.48

0.89–2.45

0.13

0.85

0.41–1.75

0.65

0.79

0.55–1.13

0.19

NIHSS

0.98

0.92–1.04

0.43

0.99

0.95–1.03

0.64

1.04

0.98–1.10

0.17

1.14

1.10–1.09

< 0.001

Stroke mechanism

SVO

ref

ref

ref

ref

LAA

0.97

0.31–3.02

0.96

1.31

0.58–3.10

0.53

1.44

0.44–4.74

0.55

1.62

0.92–2.88

0.1

CE

0.68

0.15–3.04

0.62

1.89

0.64–5.60

0.25

0.74

0.12–4.43

0.74

0.89

0.39–2.06

0.79

UD

1.16

0.36–3.72

0.80

1.73

0.72–4.15

0.22

0.32

0.07–1.58

0.16

1.18

0.64–2.17

0.6

OD

0.39

0.04–4.17

0.44

0.36

0.04–3.36

0.37

0.47

0.11–5.21

0.47

1.54

0.52–4.60

0.44

Interval from arrival to IVT

1.01

0.998–1.01

0.16

1.001

0.995–1.01

0.70

1.00

0.995–1.01

0.39

1.00

0.997–1.01

0.52

Atrial fibrillation

2.19

0.68–7.02

0.19

1.52

0.65–3.55

0.34

1.83

0.43–7.87

0.42

1.33

0.68–2.63

0.41

tPA dose

1.34

0.42–4.34

0.62

2.7

1.02–7.16

0.046

1.12

0.87–8.26

0.51

0.93

0.54–1.58

0.78

Albumin

0.23

0.11–0.51

< 0.001

0.45

0.25–0.78

0.01

1.58

0.72–3.46

0.26

1.21

0.79–1.84

0.39

Creatinine

0.99

0.60–1.64

0.97

0.88

0.59–1.33

0.56

0.71

0.30–1.65

0.42

1.49

1.05–2.12

0.03

LDL

1.01

0.996–1.01

0.31

1.00

0.996–1.01

0.43

1.01

0.995–1.02

0.32

1.00

0.999–1.01

0.15

CRP

1.01

0.99–1.02

0.29

1.01

0.997–1.02

0.15

1.00

0.99–1.02

0.64

1.01

0.996–1.02

0.28

IRG

1.00

0.996–1.01

0.68

1.00

0.998–1.01

0.31

1.00

0.99–1.01

0.73

1.00

1.00-1.01

0.10

  1. Abbreviation: PNI, prognostic nutritional index; END-SHT, symptomatic hemorrhagic transformation; HT, hemorrhagic transformation; END-prog; stroke progression; mRS, modified Rankin Scale; OR, odds ratio; CI, confidence interval; NIHSS, National Institute Health of Stroke Scale; SVO, small vessel occlusion; LAA, large artery atherosclerosis; CE, cardioembolism; UD, undetermined; OD, other determined; IVT, intravenous thrombolysis; tPA, tissue plasminogen activator; LDL, low density lipoprotein; CRP, C-reactive protein; IRG, initial random glucose