Skip to main content

Table 1 Baseline Characteristics in patients with favorable and poor outcomes

From: Low neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios predict favorable outcomes after endovascular treatment in acute basilar artery occlusion: subgroup analysis of the BASILAR registry

 

Overall n = 585

Favorable outcome n = 189

Poor outcome n = 396

P value*

P value

Age, y, median (IQR)

64 (56–73)

63 (55–71)

65 (57–73)

0.09

0.06

Male, n/total n (%)

442 (75.6)

138 (73.0)

304 (76.8)

0.21

0.32

Medical history, n/total n (%)

 Hypertension

402 (68.7)

128 (67.7)

274 (69.2)

0.12

0.72

 Hyperlipidemia

195 (33.3)

68 (36.0)

127 (32.1)

0.37

0.35

 Diabetes mellitus

134 (22.9)

29 (15.3)

105 (26.5)

0.05

0.003

 Coronary heart disease

92 (15.7)

21 (11.1)

71 (17.9)

0.34

0.03

 Atrial fibrillation

121 (20.7)

45 (23.8)

76 (119.2)

0.91

0.20

 Stroke

140 (23.9)

37 (19.6)

103 (26.0)

0.74

0.09

 Smoking

212 (36.2)

72 (38.1)

140 (35.4)

0.66

0.52

Blood pressure on admission, mmHg, median (IQR)

 Systolic

149 (133–166)

146 (130–161)

150 (134–168)

0.09

0.048

 Diastolic

84 (76–97)

84 (76–95)

85 (77–98)

0.03

0.29

 Neutrophils, median (IQR)

9.14 (6.60–11.94)

7.80 (5.96–10.22)

9.82 (7.30–12.50)

 < 0.001

 < 0.001

 Lymphocytes, median (IQR)

1.13 (0.80–1.60)

1.23 (0.90–1.65)

1.08 (0.78–1.55)

0.05

0.01

 Platelets, median (IQR)

211 (173–252)

1.08 (0.78–1.55)

215 (174–254)

0.07

0.18

 NLR, median (IQR)

7.92 (4.96–12.59)

6.26 (3.95–10.03)

9.06 (5.68–13.37)

0.002

 < 0.001

 PLR, median (IQR)

180 (128–261)

165 (123–223)

193 (130–276)

0.002

0.001

 IVT, no./total n (%)

109 (18.6)

36 (19.0)

73 (18.4)

0.83

0.86

Prestroke mRS, no./total n (%)

 0

499 (85.3)

167 (88.4)

332 (83.8)

  

 1

60 (10.3)

18 (9.5)

42 (10.6)

  

 2

26 (4.4)

4 (2.1)

22 (5.6)

  

Baseline NIHSS score, median (IQR)

27 (17–33)

18 (11–27)

30 (21–34)

 < 0.001

 < 0.001

Baseline pc-ASPECTS score, median (IQR)

8 (7–9)

9 (8–10)

7 (6–9)

 < 0.001

 < 0.001

PC-CS score, median (IQR)

5 (3–6)

5 (4–6)

4 (3–6)

0.08

 < 0.001

Occlusion sites, no./total n (%)

0.002

0.002

 BA distal

194 (33.2)

83 (43.9)

111 (28.0)

  

 BA middle

185 (31.6)

50 (26.5)

135 (34.1)

  

 BA proximal

97 (16.6)

29 (15.3)

68 (17.2)

  

 VA-V4

109 (18.6)

27 (14.3)

82 (20.7)

  

Stroke etiology, no./total n (%)

0.90

0.03

 Large artery atherosclerosis

381 (65.1)

109 (57.7)

272 (68.7)

  

 Cardioembolism

152 (26.0)

60 (31.7)

92 (23.2)

  

 Others

52 (8.9)

20 (10.6)

32 (8.1)

  

Anesthesia, no./total n (%)

223 (38.1)

64 (33.9)

159 (40.2)

0.18

0.14

First pass, no./total n (%)

303 (56.7)

123 (69.9)

180 (50.3)

0.04

 < 0.001

Workflow times, min, median (IQR)

 Onset to imaging time

209 (85–356)

200 (86–317)

210 (85–364)

0.74

0.68

 Onset to puncture time

246 (130–390)

244 (132–355)

246 (129–408)

0.76

0.77

 Puncture to recanalization time

105 (71–151)

85 (60–126)

115 (80–162)

0.001

 < 0.001

mTICI, no./total n (%)

 < 0.001

 < 0.001

 0-2a

107 (18.3)

11 (5.8)

96 (24.2)

  

 2b-3

478 (81.7)

178 (94.2)

300 (75.8)

  
  1. Abbreviations: IQR interquartile range, NLR neutrophil-to-lymphocyte ratio, PLR platelet-to-lymphocyte ratio, NIHSS National Institutes of Health Stroke Scale, pc-ASPECTS posterior- circulation Alberta Stroke Program Early CT Score, PC-CS posterior circulation collateral score, BA basilar artery, VA-V4 vertebral artery-V4 segment, mTICI modified postprocedural Thrombolysis in Cerebral Infarction
  2. *Adjusted estimates of effect were calculated using multiple regression taking the following variables into account: age, diabetes mellitus, puncture to recanalization time, NIHSS, pc-ASPECTS, occlusion sites, TOAST
Back to article page

BMC Neurology

ISSN: 1471-2377

Contact us