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Table 2 Post vs. Pre-nabiximols exposure contrast in region-of-interest connections (all patients)

From: Resting-state functional connectivity in multiple sclerosis patients receiving nabiximols for spasticity

Analysis Unit

Statistic

p-unc

p-FDR

Cereb45 r -ICC r

T(9) = 6.93

0.0000

0.0057

ICC r -Cereb45 r

T(9) = 6.93

0.0000

0.0057

MidFG r -pSTG l

T(9) = 6.17

0.0001

0.0137

pSTG l -MidFG r

T(9) = 6.17

0.0001

0.0137

pTFusC r -aMTG r

T(9) = 6.12

0.0001

0.0145

aMTG r -pTFusC r

T(9) = 6.12

0.0001

0.0145

Ver6 -OP r

T(9) = 5.30

0.0002

0.0412

OP r -Ver6

T(9) = 5.30

0.0002

0.0412

Cereb45 r -(165)

T(9) = 4.72

0.0005

0.0454

  1. Region-of-interest (ROI) connections with threshold ROI to ROI connection by intensity at a 0.05 one-sided (positive) FDR-P value and threshold seed ROIs at a 0.05 uncorrected P value
  2. Abbreviations: FDR False discovery rate, l left, r right, Cereb45 Cerebellum 4 5, ICC Intracalcarine Cortex, MidFG Middle Frontal Gyrus, pSTG Superior Temporal Gyrus posterior division, pTFusC Temporal Fusiform Cortex posterior division, aMTG Middle Temporal Gyrus anterior division, Ver6 vermis 6, OP Occipital Pole; 165, networks.Cerebellar.Posterior