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Table 1 Univariate analysis of 90⁃day functional independence (mRS ≤ 2) in mechanical thrombectomy patients

From: New stress-induced hyperglycaemia markers predict prognosis in patients after mechanical thrombectomy

 

All patients

(n = 423)

Good outcomes

(n = 231)

Poor outcomes

(n = 192)

P-value

[year, M (Q1, Q3)]

70(62,77)

68(58,75)

74(66,78)

< 0.001

Male [n, (%)]

250(59.1)

154(66.7)

96(50.0)

0.001

Medical history [n, (%)]

    

Hypertension

269(63.6)

134(58.0)

135(70.3)

0.009

Diabetes mellitus

59(13.9)

26(11.3)

33(17.2)

0.080

Atrial fibrillation

221(52.2)

97(42.0)

124(64.6)

< 0.001

Antiplatelets/anticoagulants history [n, (%)]

   

0.523

No

340(80.4)

188(81.4)

152(79.2)

 

Antiplatelets

58(13.7)

28(12.1)

30(15.6)

 

Anticoagulants

25(5.9)

15(6.5)

10(5.2)

 

IT [n, (%)]

53(12.1)

28(12.1)

23(12.0)

0.964

Baseline SBPa[mmHg, M (Q1, Q3)]

152(139,168)

150(138,165)

156(140,172)

0.033

Baseline DBPb[mmHg, M (Q1, Q3)]

83(74,92)

83(74,92)

82(74,93)

0.708

Admission NIHSS [M (Q1, Q3)]

14(11,17)

12(10,15)

15(12,19)

< 0.001

Admission ASPECT [M (Q1, Q3)]

9(7,10)

9(8,10)

8(6,9)

< 0.001

TOAST classification [n, (%)]

   

< 0.001

LAA

119(28.1)

87(37.7)

32(16.7)

 

Cardioembolic

257(60.8)

116(50.2)

141(73.4)

 

Others

47(11.1)

28(12.1)

19(9.9)

 

Occlusion location [n, (%)]

   

0.036

ICA

164(38.8)

78(33.8)

86(44.8)

 

MCA(M1)

216(51.1)

131(56.7)

85(44.3)

 

MCA(M2)

43(10.2)

22(9.5)

21(10.9)

 

OTP [min, M (Q1, Q3)]

300(230,390)

300(221,360)

300(240,392)

0.424

OTRc [min, M (Q1, Q3)]

356(280,456)

350(270,454)

360(300,493)

0.105

Collateral scored [n, (%)]

   

< 0.001

Grade 0

49(11.6)

5(2.2)

44(22.9)

 

Grade 1

101(24.0)

43(18.8)

58(30.2)

 

Grade 2

271(64.4)

181(79.0)

90(46.9)

 

mTICI,2b/3 [n, (%)]

379(89.6)

216(93.5)

163(84.9)

0.004

SHR [M (Q1, Q3)]

0.87(0.76,1.05)

0.83(0.72,0.94)

0.97(0.83,1.13)

< 0.001

GG [M (Q1, Q3)]

− 0.84 (-1.67,0.33)

-1.81(-1.07,-0.50)

-1.26 (-0.17,0.86)

< 0.001

SHR (> 0.89) [n, (%)]

191(45.2)

69(29.9)

122(63.5)

< 0.001

GG (>-0.53) [n, (%)]

169(40.0)

59(25.5)

110(57.3)

< 0.001

  1. Abbreviations: mRS, modified Rankin Scale score; SBP, systolic blood pressure; DBP, diastolic blood pressure; 1mmHg = 0.133 kPa; IT, Intravenous Thrombolysis; NIHSS, National Institutes of Health Stroke Scale; ASPECT, Alberta Stroke Program Early CT; TOAST, Trial of Org 10172 in Acute Stroke Treatment; LAA, large-artery atherosclerosis; ICA, internal carotid artery; MCA(M1/M2) M1/M2 middle cerebral artery segment, OTP, onset-to-puncture time; OTR, onset-to-reperfusion time; mTICI, modified Thrombolysis in Cerebral Infarction; SHR, stress hyperglycaemia ratio; GG, glycaemic gap
  2. a:13 patients lost data on SBP
  3. b:13 patients lost data on DBP
  4. c:1 patient lost data on OTR
  5. d:2 patients lost data on Collateral score