Table 1 Comparison of baseline characteristics between antithrombotic medication usage groups
Total (n = 2,285) | Antiplatelet only (n = 1,829) | Anticoagulant only (n = 252) | Combination therapy (n = 204) | P-value | |
|---|---|---|---|---|---|
Age | 68.94 ± 10.24 | 69.05 ± 10.14 | 67.84 ± 10.86 | 69.39 ± 10.31 | 0.174 |
Age group | |||||
Young age (19–54) | 214 (9.37) | 169 (9.24) | 25 (9.92) | 20 (9.80) | 0.908 |
Middle age (55–74) | 1,341 (58.69) | 1,071 (58.56) | 153 (60.71) | 117 (57.35) | |
Old age (75-) | 730 (31.95) | 589 (32.20) | 74 (29.37) | 67 (32.84) | |
Sex | |||||
Male | 1,581 (69.19) | 1,294 (70.75) | 149 (59.13) | 138 (67.65) | < 0.001 |
Female | 704 (30.81) | 535 (29.25) | 103 (40.87) | 66 (32.35) | |
Hypertension | 1,563 (68.40) | 1,261 (68.94) | 169 (67.06) | 133 (65.2) | 0.490 |
Diabetes mellitus | 633 (27.70) | 532 (29.09) | 52 (20.63) | 49 (24.02) | 0.009 |
Dyslipidemia | 601 (26.30) | 488 (26.68) | 69 (27.38) | 44 (21.57) | 0.266 |
Atrial fibrillation | 221 (9.67) | 65 (3.55) | 105 (41.67) | 51 (25) | < 0.001 |
Coronary artery disease | 699 (30.59) | 538 (29.41) | 85 (33.73) | 76 (37.25) | 0.036 |
Heart failure | 194 (8.49) | 130 (7.11) | 35 (13.89) | 29 (14.22) | < 0.001 |
Valvular heart disease | 28 (1.23) | 12 (0.66) | 11 (4.37) | 5 (2.45) | < 0.001 |
Deep vein thrombosis | 31 (1.36) | 23 (1.26) | 5 (1.98) | 3 (1.47) | 0.639 |
Pulmonary thromboembolism | 16 (0.70) | 7 (0.38) | 6 (2.38) | 3 (1.47) | < 0.001 |
Gastro-intestinal ulcer | 1,526 (66.78) | 1,237 (67.63) | 160 (63.49) | 129 (63.24) | 0.225 |
Outcome | |||||
Anemia due to acute bleeding | 68 (2.98) | 58 (3.17) | 5 (1.98) | 5 (2.45) | 0.523 |
Intracranial hemorrhage | 119 (5.21) | 91 (4.98) | 17 (6.75) | 11 (5.39) | 0.491 |
Gastrointestinal bleeding | 671 (29.37) | 40 (2.19) | 7 (2.78) | 7 (3.43) | 0.486 |
Major bleeding | 774 (33.87) | 56 (3.06) | 10 (3.97) | 8 (3.92) | 0.633 |
Death | 1,531 (67.00) | 1,212 (66.27) | 185 (73.41) | 134 (65.69) | 0.071 |
Cancer type | |||||
Gastric cancer (C16) | 276 (12.08) | 236 (12.90) | 22 (8.73) | 18 (8.82) | 0.053 |
Colorectal cancer (C18-20) | 346 (15.14) | 266 (14.54) | 45 (17.86) | 35 (17.16) | 0.272 |
Liver cancer (C22) | 179 (7.83) | 142 (7.76) | 19 (7.54) | 18 (8.82) | 0.852 |
Pancreas cancer (C25) | 101 (4.42) | 76 (4.16) | 14 (5.56) | 11 (5.39) | 0.466 |
Lung cancer (C34) | 400 (17.51) | 323 (17.66) | 41 (16.27) | 36 (17.65) | 0.861 |
Breast cancer (C50) | 123 (5.38) | 95 (5.19) | 15 (5.95) | 13 (6.37) | 0.711 |
Prostate cancer (C61) | 190 (8.32) | 153 (8.37) | 23 (9.13) | 14 (6.86) | 0.674 |