Table 1 Clinical and biochemical characteristics of the good and poor outcomes in all AIS patients
Variables | Total (n = 649) | Good outcome (n = 557) | Poor outcome (n = 92) | P | |
|---|---|---|---|---|---|
Age, Median (IQR) | 69.0 (60.0, 77.0) | 67.0 (59.0, 76.0) | 76.0 (68.8, 84.0) | < 0.001 | |
Hospital stay (days), Mean ± SD | 13.3 ± 4.1 | 13.0 ± 3.6 | 14.8 ± 6.1 | < 0.001 | |
Sex, n (%) | Male | 427 (65.8) | 378 (67.9) | 49 (53.3) | 0.009 |
Female | 222 (34.2) | 179 (32.1) | 43 (46.7) | ||
Risk factors, n (%) | |||||
Hypertension | yes | 490 (75.5) | 417 (74.9) | 73 (79.3) | 0.426 |
no | 159 (24.5) | 140 (25.1) | 19 (20.7) | ||
Diabetes Mellitus | yes | 272 (41.9) | 219 (39.3) | 53 (57.6) | 0.001 |
no | 377 (58.1) | 338 (60.7) | 39 (42.4) | ||
Atrial Fibrillation | yes | 73 (11.2) | 51 (9.2) | 22 (23.9) | < 0.001 |
no | 576 (88.8) | 506 (90.8) | 70 (76.1) | ||
Hyperlipidemia | yes | 35 (5.4) | 31 (5.6) | 4 (4.3) | 0.805 |
no | 613 (94.6) | 525 (94.4) | 88 (95.7) | ||
Coronary heart disease | yes | 123 (19.0) | 99 (17.8) | 24 (26.1) | 0.082 |
no | 526 (81.0) | 458 (82.2) | 68 (73.9) | ||
Smoking | yes | 196 (30.2) | 179 (32.1) | 17 (18.5) | 0.012 |
no | 453 (69.8) | 378 (67.9) | 75 (81.5) | ||
Drinking | yes | 127 (19.6) | 115 (20.6) | 12 (13) | 0.119 |
no | 522 (80.4) | 442 (79.4) | 80 (87) | ||
Biochemical variables, Median (IQR) | |||||
Total-C | 4.3 (3.4, 5.1) | 4.3 (3.5, 5.1) | 3.8 (3.0, 5.0) | 0.012 | |
TG | 1.3 (1.0, 1.7) | 1.3 (1.0, 1.7) | 1.1 (0.9, 1.5) | 0.005 | |
HDL-C | 1.2 (1.0, 1.4) | 1.2 (1.0, 1.4) | 1.2 (1.0, 1.5) | 0.876 | |
LDL-C | 2.5 (1.9, 3.1) | 2.6 (1.9, 3.2) | 2.2 (1.6, 3.0) | 0.011 | |
TOAST classification, n (%) | < 0.001 | ||||
LAA | 301 (46.4) | 250 (44.9) | 51 (55.4) | ||
SVO | 254 (39.1) | 237 (42.5) | 17 (18.5) | ||
CE | 79 (12.2) | 57 (10.2) | 22 (23.9) | ||
OE and UD | 15 (2.3) | 13 (2.3) | 2 (2.2) | ||
BP, n (%)/Mean ± SD | |||||
Admission SBP | 145.0 (132.0,162.0) | 146.0 (133.0,161.0) | 141.5 (126.5166.5) | 0.782 | |
Admission DBP | 84.0 (75.0, 93.0) | 84.0 (76.0, 92.0) | 82.0 (73.8, 94.0) | 0.363 | |
Mean SBP | 142.7 (133.0,151.8) | 142.9 (133.7151.2) | 141.6 (130.0,154.5) | 0.736 | |
Mean DBP, Mean ± SD | 81.7 ± 9.0 | 82.1 ± 9.0 | 79.1 ± 9.1 | 0.002 | |
BP indices in acute stage (1–4d), Mean ± SD | |||||
Mean SBP | 144.8 ± 16.4 | 144.6 ± 15.6 | 145.6 ± 20.6 | 0.618 | |
Mean DBP | 82.6 ± 9.7 | 82.9 ± 9.6 | 80.5 ± 10.3 | 0.027 | |
BP indices in subacute stage (>4 d), n (%)/Mean ± SD | |||||
Mean SBP | 142.3 (132.2151.2) | 142.4 (133.3151.1) | 141.3 (128.5152.4) | 0.563 | |
Mean DBP | 81.4 ± 9.3 | 81.9 ± 9.2 | 78.3 ± 9.3 | < 0.001 | |
Previous medication history, n (%) | |||||
Antihypertensive drugs | yes | 365 (56.2) | 316 (56.7) | 49 (53.3) | 0.611 |
no | 284 (43.8) | 241 (43.3) | 43 (46.7) | ||
Hypoglycemic agents | yes | 199 (30.7) | 158 (28.4) | 41 (44.6) | 0.005 |
no | 449 (69.2) | 398 (71.5) | 51 (55.4) | ||
Statins | yes | 97 (14.9) | 78 (14) | 19 (20.7) | 0.134 |
no | 552 (85.1) | 479 (86) | 73 (79.3) | ||
Antiplatelet drugs | yes | 120 (18.5) | 95 (17.1) | 25 (27.2) | 0.03 |
no | 529 (81.5) | 462 (82.9) | 67 (72.8) | ||
Admission assessment, n (%) | |||||
NIHSS | 2.0 (1.0, 5.0) | 2.0 (1.0, 4.0) | 8.5 (5.0, 12.0) | < 0.001 | |
mRS | 2.0 (1.0, 3.0) | 1.0 (1.0, 3.0) | 4.0 (4.0, 5.0) | < 0.001 | |
END | yes | 90 (13.9) | 64 (11.5) | 26 (28.3) | < 0.001 |
no | 559 (86.1) | 493 (88.5) | 66 (71.7) | ||