Table 1 Clinical characteristics of study patients with glioma
Characteristics | Grade II or III glioma | GBM | Total | p |
|---|---|---|---|---|
Number, (%) | 515 (49.5) | 525 (50.5) | 1040 | |
Sex, female, n (%) | 230 (44.7) | 205 (39.0) | 435 (41.8) | 0.067 |
Age at diagnosis of glioma, mean ± SD, y | 42.9 ± 13.4 | 57.7 ± 14.6 | 50.4 ± 15.8 | < 0.001 |
Time between glioma diagnosis and death (months), mean ± SD | 31.7 ± 31.5 | 17.0 ± 18.0 | 24.3 ± 26.6 | < 0.001 |
Time between glioma diagnosis and disease progression (months), mean ± SD | 25.8 ± 25.7 | 10.2 ± 13.0 | 17.9 ± 21.7 | < 0.001 |
WHO-grade glioma, n (%) | N/A | |||
Grade II | 250 (48.5) | N/A | 250 (24.0) | |
Grade III | 265 (51.5) | 265 (25.5) | ||
Grade IV | N/A | 525 (100) | 525 (50.5) | |
Glioma histological type, n (%) | N/A | |||
Astrocytoma | 194 (37.7) | N/A | 194 (18.7) | |
Oligodendroglioma | 191 (37.1) | 191 (18.4) | ||
Oligoastrocytoma | 130 (25.2) | 130 (12.5) | ||
Glioblastoma | N/A | 525 (100) | 525 (50.5) | |
IDH1 mutation, n (%) | < 0.001 | |||
Yes | 91 (17.7) | 14 (2.7) | 105 (10.1) | |
No | 34 (6.6) | 230 (43.8) | 264 (25.4) | |
Missing data | 390 (75.7) | 281 (53.5) | 671 (64.5) | |
Karnofsky Performance Scale Index, median (IQR) | 80.0 (80.0–90.0) | 80.0 (70.0–80.0) | 80.0 (80.0–90.0) | < 0.001 |
Missing data, n (%) | 52 (10.1) | 133 (25.3) | 185 (17.8) | |
Radiation treatment, n (%) | < 0.001 | |||
Yes | 296 (57.5) | 435 (82.9) | 731 (70.3) | |
No | 185 (35.9) | 70 (13.3) | 255 (24.5) | |
Missing data | 34 (6.6) | 20 (3.8) | 54 (5.2) |