Table 1 .
| Â | MOCA at Discharge | MOCA at 90 Days | ||
|---|---|---|---|---|
|  | Overall Cohort n = 52 | Proteomic Cohort n = 23 | Overall Cohort n = 28 | Proteomic Cohort n = 13 |
Age (median; range) | 62 ± 14.7 | 59 ± 15.1 | 60 ± 16.5 | 59 ± 18.7 |
Sex | ||||
 Female | 29 (56) | 15 (65) | 10 (36) | 5 (38) |
 Male | 23 (44) | 8 (35) | 18 (64) | 8 (62) |
BMI | ||||
 < 18.5 | 2 (4) | 1 (4) | 0 (0) | 0 (0) |
 18.5–24.9 | 10 (19) | 5 (22) | 5 (18) | 2 (15) |
 25–29.9 | 15 (29) | 8 (35) | 9 (32) | 6 (46) |
 > 30 | 25 (48) | 9 (39) | 14 (50) | 5 (38) |
Comorbidities | ||||
 Hypertension | 42 (81) | 18 (78) | 23 (82) | 11 (85) |
 Diabetes Mellitus II | 14 (27) | 2 (9) | 6 (21) | 2 (15) |
 Hyperlipidemia | 16 (31) | 5 (22) | 8 (29) | 4 (31) |
 Atrial Fibrillation | 20 (38) | 10 (36) | 9 (39) | 5 (38) |
 Previous Stroke | 6 (12) | 3 (13) | 1 (4) | 0 (0) |
Smoking Status* | ||||
 Never | 25 (48) | 11 (52) | 12 (52) | 6 (50) |
 Currently | 17 (33) | 8 (38) | 8 (35) | 5 (42) |
 Previously (> 6 months) | 6 (2) | 2 (10) | 3 (13) | 1 (8) |
NIHSS on Admission | ||||
 Minor Stroke (1–4) | 3 (6) | 1 (4) | 2 (7) | 1 (8) |
 Moderate Stroke (5–15) | 32 (63) | 17 (74) | 15 (54) | 7 (54) |
 Moderate/Severe (16–20) | 10 (19) | 4 (17) | 7 (25) | 4 (30) |
 Severe Stroke (≥ 21) | 6 (12) | 1 (4) | 4 (14) | 1 (8) |
NIHSS at Discharge* | ||||
 Minor Stroke (1–4) | 38 (74) | 16 (70) | 16 (59) | 6 (50) |
 Moderate Stroke (5–15) | 12 (24) | 6 (26) | 10 (37) | 5 (42) |
 Moderate/Severe (16–20) | 1 (2) | 1 (4) | 1 (4) | 1 (8) |
 Severe Stroke (≥ 21) | 0 (0) | 0 (0) | 0 (0) | 0 (0) |
TICI Score | ||||
 2A =  < 50% Perfusion | 0 (0) | 0 (0) | 0 (0) | 0 (0) |
 2B =  > 50% Perfusion | 19 (37) | 9 (39) | 11 (44) | 6 (46) |
 3 = Full Perfusion | 32 (63) | 14 (61) | 14 (56) | 7 (54) |
LKN to Thrombectomy | 564 ± 356 | 657 ± 405 | 625 ± 402 | 796 ± 460 |
Infarct Volume (mm3) | 22,353 ± 27,183 | 15,991 ± 18,015 | 32,808 ± 37,961 | 27,403 ± 36,709 |
Location of Thombus | ||||
 Left ICA | 2 (4) | 1 (4) | 1 (4) | 1 (8) |
 Right ICA | 1 (2) | 0 (0) | 0 (0) | 0 (0) |
 Left MCA | 16 (30) | 6 (26) | 8 (28) | 1 (8) |
 Right MCA | 28 (54) | 14 (61) | 14 (50) | 9 (69) |
 Basilar | 5 (10) | 2(9) | 5 (18) | 2 (15) |
Source of Thrombus | ||||
 Cardioembolic | 32 (61) | 14 (59) | 15 (53) | 7 (53) |
 Atherembolic | 14 (27) | 3 (13) | 7 (25) | 2 (15) |
 Intracranial Stenosis | 1 (2) | 1 (5) | 1 (5) | 1 (8) |
 Dissection | 1 (2) | 1 (5) | 1 (5) | 1 (8) |
 Carotid Occlusion | 1 (2) | 1 (5) | 1 (5) | 1 (8) |
 Infection | 0 (0) | 0 (0) | 0(0) | 0 (0) |
 Unknown | 3 (6) | 3 (13) | 2 (7) | 1 (8) |
CTA Collateral Score* | ||||
 0 | 2 (9) | 2 (10) | 4 (24) | 3 (25) |
 1 | 15 (68) | 14 (70) | 10 (58) | 7 (58) |
 2 | 3 (14) | 2 (10) | 2 (12) | 2 (17) |
 3 | 2 (9) | 2 (10) | 1 (6) | 0 (0) |
|  | *missing 1 (n = 51) | *missing 2 (n = 23) | *missing 5 (n = 23) | *missing 1 (n = 12) |
|  | **missing 3 (n = 49) | **missing 1 (n = 24) | **missing 1 (n = 27) |  |
|  | ***missing 7 (n = 45) | ***missing 3 (n = 22) | ***missing 3 (n = 25) |  |
|  | ****missing 10 (n = 42) |  | ****missing 9 (n = 19) |  |
|  |  |  | *****missing 11 (n = 17) |  |