Fig. 1
Comparison of ECAS absolute outcome scores of patients with SMA type 2 and 3 before treatment initiation (V0)
A, B, C: Box plots of the ALS-specific domains in patients with SMA type 2 compared to patients with SMA type 3. D, E: Box plots of the non-ALS-specific domains in patients with SMA type 2 compared to patients with SMA type 3. F, G: Box plots of ECAS subscores in patients with SMA type 2 compared to patients with SMA type 3. H: Boxplot of ECAS total score in patients with SMA type 2 compared to patients with SMA type 3. ALS: amyotrophic lateral sclerosis; ECAS: Edinburgh Cognitive and Behavioral ALS Screen; SMA: spinal muscular atrophy. Box plots show median (horizontal line), inter-quartile range (boxes) and scores outside of inter-quartile range (whiskers). Calculated by Mann-Whitney U-test. Significance levels: ** p < 0.01; ns: statistically not significant.