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Fig. 4 | BMC Neurology

Fig. 4

From: Lymphoproliferative disorder during temozolomide therapy; a representative case of a formidable complication and management challenges

Fig. 4

Histopathological investigation of an enlarged cervical lymph node revealed dense infiltration of lymphocytes, and the normal lymph node architecture was widely effaced (A). Infiltration of small to medium-sized lymphocytes, plasma cells and histiocytes was observed (B). Large, atypical lymphocytes with prominent nucleoli were sparsely observed. These large lymphocytes were positive for CD20 (C) and PAX5 (D). Epstein-Barr virus (EBV) DNA was confirmed by in-situ hybridization (E)

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BMC Neurology

ISSN: 1471-2377

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