Plasma neurofilament light admission levels and development of axonal pathology in mild traumatic brain injury

BMC Neurology

Table 3 Correlation between admission neurofilament light (NF-L) levels and diffusion measures (adjusted for age and sex)

		FA		MD		AD		RD
Group	Number of patients	Spearman’s rho	p-value	Spearman’s rho	p-value	Spearman’s rho	p-value	Spearman’s rho	p-value
all mTBI	93	-0.323	0.002	0.343	p < 0.001	0.313	0.003	0.324	0.002
CT-Negative	53	-0.032	0.825	0.194	0.172	0.214	0.132	0.163	0.252
CT-Positive	40	-0.389	0.016	0.408	0.011	0.453	0.004	0.4	0.013
Complete recovery	35	-0.184	0.306	0.182	0.311	0.044	0.808	0.179	0.318
Incomplete recovery	58	-0.367	0.005	0.395	0.003	0.394	0.003	0.35	0.008
CT-Negative with complete recovery	29	-0.131	0.562	0.22	0.325	0.131	0.561	0.223	0.318
CT-Negative with incomplete recovery	24	0.032	0.873	0.078	0.699	0.216	0.278	0.060	0.766

Computed tomography negative (CT-negative) = Marshall 1, Computed tomography positive (CT-positive) = Marshall 2–6. Glasgow Outcome Scale Extended (GOSE) 8 = complete recovery, Glasgow Outcome Scale Extended (GOSE) 1–7 = incomplete recovery. FA Fractional anisotropy, MD Mean diffusivity, AD Axial diffusivity, RD Radial diffusivity

ISSN: 1471-2377