Table 2 Number and timing of querying of demographics, exposures and outcomes

Informed consent

1

X

Demographics

Age

1

X

X

MS type diagnosed

2

X

X

X

X

X

MS duration

2

X

X

X

X

X

Do you follow a MS-specific lifestyle program?

2

X

X

X

X

X

Do you follow a MS-specific diet

2

X

X

X

X

X

Sex and gender

2

X

Residential address and country

1

X

X

Country of birth

1

X

Height/weight

2

X

X

X

X

Comorbidities (yes and specify)

2

X

X

X

X

Marital status

1

X

X

X

X

Education

1

X

Employment status

1

X

X

X

X

Alcohol and smoking

5

X

X

X

X

Medications

4

X

X

X

X

Perceived Social Support

12

X

X

X

X

Exposures

Physical activity: IPAQ-SF

7

X

X

X

X

Meditation: MAQ

3

X

X

X

X

Sun exposure

4

X

X

X

X

Diet quality: DHQ

22

X

X

X

X

Consumption of meat or dairy

2

X

X

X

X

Omega-3 intake: dose, frequency

2

X

X

X

X

Vitamin D intake: dose, frequency

2

X

X

X

X

Health outcomes

HRQOL: MSQOL-54

54

X

X

X

X

Disability: PDDS

1

X

X

X

X

Anxiety and depression: HADS

14

X

X

X

X

Fatigue: FSS

9

X

X

X

X

Self-efficacy: UWSE-6

6

X

X

X

X

Qualitative interviewing

(7)

X

X

If clinically significant improvement in HRQOL subset scores in Intervention group from baseline, we will consider an amendment to the RCT to provide participants in the SCC access to the IC

X

If no clinically significant improvement in HRQOL subset scores in IC from baseline, the RCT will not be amended

X

Total no. quantitative data questions

166

154

162

158

(not including qualitative)