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Table 2 Univariate and multivariate analysis via binary logistic regression of variables associated with recurrent infection of MG

From: Myasthenia gravis and independent risk factors for recurrent infection: a retrospective cohort study

 

Crude OR

[95% CI]

Adjusted OR

[95% CI]

P-value

Adjusted

P-value

Male

1.17 [0.71–1.94]

-

0.536

-

Age

1.02 [1.00–1.03]

0.93 [0.87–1.01]

0.028*

0.101

Respiratory and bulbar function

 V5

0.34 [0.17–0.67]

0.34 [0.01–15.48]

0.002**

0.582

 VE

3.57 [1.56–8.16]

0.16 [0.00–9.54]

0.003**

0.379

Motor scale (MRC)

 Bil. deltoid and iliopsoas

0.94 [0.88–1.01]

-

0.101

-

Concomitant diseases

 Diabetes mellitus

2.61 [1.32–5.16]

83.11 [1.25–5512.32]

0.006**

0.039*

 Deep vein thrombosis

9.62 [1.11–83.5]

4.75 [0.05–464.08]

0.040*

0.505

 Thymic cancer

2.22 [1.17–4.19]

1.67 [0.12–22.99]

0.014*

0.702

Duration of hospitalization

1.03 [1.01–1.05]

1.14 [1.02–1.26]

0.006**

0.015*

Foley catheterization

0.61 [0.34–1.04]

-

0.069

-

Ventilator dependency

0.77 [0.44–1.37]

-

0.375

-

Plasmapheresis

1.83 [1.01–3.30]

0.33 [0.03–4.00]

0.045*

0.386

AChR-antibody positive

1.89 [0.98–3.68]

-

0.059

-

Laboratory data

 Hb

0.88 [0.78–1.00]

1.04 [0.56–1.94]

0.037*

0.891

 Creatinine

1.08 [0.90–1.30]

-

0.385

-

 K

0.49 [0.28–0.85]

0.22 [0.01–2.43]

0.011*

0.215

 Mg

0.16 [0.03–0.89]

0.01 [0.00–0.54]

0.037*

0.024*

 Albumin

0.63 [0.41–0.96]

0.47 [0.07–3.26]

0.030*

0.449

 APTT

1.08 [1.01–1.16]

1.96 [1.03–3.70]

0.026*

0.038*

 Cortisol

0.96 [0.91–1.00]

-

0.065

-

  1. AChR acetylcholine receptor, APTT activated partial thromboplastin time, Bil. Bilateral, GCS Glasgow coma scale, Hb hemoglobin, K potassium, MG myasthenia gravis, Mg magnesium, MRC Medical Research Council scale, V5 oriented to verbal response of GCS and no significant respiratory distress and bulbar impairment, VE difficulty in evaluating GCS due to endotracheal intubation indicating severe bulbar impairment or respiratory distress. Risk for recurrent infection in MG patients was presented as odds ratio (OR). 95% CI, 95% confidence interval. A p-value below 0.05 was considered statistically significant. *p < 0.05; **p < 0.01