Fig. 1

Brain MRI (T2-FLAIR) performed in November 2021 shows multiple hyperintense white matter lesions adjacent to the bilateral ventricle, at the bilateral frontal lobe, and at the right centrum semiovale and venous developmental anomaly at the left frontal lobe (A–C). DWI shows no abnormalities. Axial cervical (T2) and thoracic (T2-FS) spinal MRI present multiple hyperintense patchy lesions along the cervical and thoracic segments (D–F). Sagittal MRI (T2–FS) shows banded lesions along the thoracic and cervical cord at the C4–C6 and T2–T9 levels (G, H). Strong signals are not present on enhancing MRI. Red arrowheads indicate the lesions. DWI, diffusion-weighted imaging; MRI, magnetic resonance imaging; T2, T2-weighted imaging; T2-FLAIR, T2-weighted fluid-attenuated inversion recovery imaging; T2-FS, fat-saturated T2-weighted imaging