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Fig. 1 | BMC Neurology

Fig. 1

From: Elevated SIRT2 of serum exosomes is positively correlated with diagnosis of acute ischemic stroke patients

Fig. 1

(A) Exosomes protein marker of CD63 and CD81 were detected in serum and serum exosomes by western blot. Full-length blots/gels are presented in the Supplementary Fig. 1. (B) Serum exosome SIRT2 concentration in control group (n = 75), AIS group (n = 75), NIHSS < 4 (n = 23), NIHSS ≥ 4 (n = 52), mRS < 3 (n = 52), and mRS ≥ 3(n = 23) group. (C) Receiver operating characteristic (ROC) curve of the relationship between Serum exosome SIRT2 concentration and acute ischemic stroke. (D) Receiver operating characteristic (ROC) curve of the relationship between Serum exosome SIRT2 concentration and NIHSS ≥ 4 acute ischemic stroke. (E) Receiver operating characteristic (ROC) curve of the relationship between Serum exosome SIRT2 concentration and mRS ≥ 3 acute ischemic stroke. (F) The correlation between serum exosome SIRT2 concentration and mRS score of AIS by restricted cubic spline analysis. *p < 0.05 ***p < 0.001

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BMC Neurology

ISSN: 1471-2377

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