Table 2 Distribution of baseline characteristics in relation to the severity of CAC
From: Is coronary artery calcium an independent risk factor for white matter hyperintensity?
Variable | Zero (CACS, 0) | Low (CACS, 1–99) | Middle (CACS, 100–399) | High (CACS, ≥ 400) | P | Post hoc |  | |||
|---|---|---|---|---|---|---|---|---|---|---|
n | 144 (42.1) | 44 (12.9) | 62 (18.1) | 92 (26.9) | Â | Â | ||||
Age, y (mean ± SD)* | 62.3 ± 1.6 | 64.1 ± 2.3 | 71.1 ± 2.8 | 80.9 ± 5.8 | < 0.001 | a, b, c, d, e, f |  | |||
Sex, female** | 73 (50.7) | 20 (45.5) | 26 (41.9) | 41 (44.6) | 0.303 | Â | Â | |||
Hypertension** | 54 (37.5) | 19 (43.2) | 28 (45.2) | 53 (57.6) | 0.003 | a, b | Â | |||
Diabetes** | 37 (25.7) | 17 (38.6) | 27 (43.5) | 41 (44.6) | 0.010 | b, c, d | Â | |||
Smoking** | 19 (13.2) | 17 (38.6) | 26 (41.9) | 42 (45.7) | < 0.001 | a, b, c |  | |||
Alcohol consumption** | 17 (11.8) | 3 (6.8) | 11 (17.7) | 16 (17.3) | 0.250 | a, b, c | Â | |||
Heart disease** | 11 (7.6) | 6 (13.6) | 10 (16.1) | 19 (20.7) | 0.030 | c | Â | |||
Hypercholesterolemia** | 18 (12.5) | 10 (22.7) | 13 (21.0) | 14 (15.2) | 0.050 | Â | Â | |||
Body mass index (kg/m²)* | 23.1 ± 3.3 | 23.4 ± 3.1 | 23.8 ± 2.9 | 24.1 ± 3.2 | 0.115 | c |  | |||
Total WMH volume* | 0.3 (0.2–0.4) | 0.6 (0.4–0.9) | 2.8 (2.2–3.8) | 10.0 (6.5–14.8) | < 0.001 | a, b, c, d, e, f |  | |||