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Table 5 Full field Electroretinography (ff-ERG) responses in PD patients compared to healthy controls

From: Retinal functional and structural changes in patients with Parkinson’s disease

 

PD patients [mean (SD)] (n = 50)

Controls [mean (SD)] (n = 50)

P-value

Dark-adapted ERG (rod response)

 RT eye

a wave

Latency (milliseconds)

19.46 (3.66)

17.11(0.88)

< 0.001*

Amplitude (µV)

35.87(7.92)

43.70(1.68)

< 0.001*

b wave

Latency (milliseconds)

38.15(3.61)

34.33(0.92)

< 0.001*

Amplitude (µV)

43.60(12.29)

64.60(1.85)

< 0.001*

 LT eye

a wave

Latency (milliseconds)

19.75(3.94)

17.02(0.86)

< 0.001*

Amplitude (µV)

35.46(8.09)

43.60(1.78)

< 0.001*

b wave

Latency (milliseconds)

38.41(4.03)

34.40(0.94)

< 0.001*

Amplitude (µV)

42.92(12.77)

65.02(2.51)

< 0.001*

Light-adapted ERG (cone response)

 RT eye

a wave

Latency (milliseconds)

18.53 ± 2.37

17.17(0.75)

< 0.001*

Amplitude (µV)

8.36(4.82)

24.7(2.64)

< 0.001*

b wave

Latency (milliseconds)

38.39(2.29)

33.70(1.62)

< 0.001*

Amplitude (µV)

26.52(8.86)

51.13(6.61)

< 0.001*

 LT eye

a wave

Latency (milliseconds)

18.57(2.58)

16.97(0.78)

< 0.001*

Amplitude (µV)

8.34(4.60)

24.39(2.81)

< 0.001*

b wave

Latency (milliseconds)

38.41(2.37)

33.78(1.57)

< 0.001*

Amplitude (µV)

27.12(8.94)

50.76(7.24)

< 0.001*

  1. PD Parkinson’s disease
  2. *P-value ≤ 0.05 is considered significant