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Table 3 The JBI critical appraisal tool for cohort studies

From: SIMOA-based analysis of plasma NFL levels in MCI and AD patients: a systematic review and meta-analysis

Study

Q1

Q2

Q3

Q4

Q5

Q6

Q7

Q8

Q9

Yes %

Risk of bias

Mattsson et al.

Yes

Yes

Yes

Yes

Yes

Yes

Yes

Yes

Yes

100%

Low

  1. Q1. Were the groups comparable other than the presence of disease in cases or the absence of disease in controls?    Q5. Was exposure measured in the same way for cases and controls?
  2. Q2. Were cases and controls matched appropriately?
  3. Q3. Were the same criteria used for the identification of cases and controls
  4. Q4. Was exposure measured in a standard, valid and reliable way?
  5. Q6. Were confounding factors identified?
  6. Q7. Were strategies to deal with confounding factors stated?
  7. Q8. Were outcomes assessed in a standard, valid and reliable way for cases and controls?
  8. Q9. Was the exposure period of interest long enough to be meaningful?
  9. Q10. Was appropriate statistical analysis used?