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Table 4 The JBI critical appraisal tool for case–control studies

From: SIMOA-based analysis of plasma NFL levels in MCI and AD patients: a systematic review and meta-analysis

Study

Q1

Q2

Q3

Q4

Q5

Q6

Q7

Q8

Q9

Q10

Q11

Yes %

Risk of bias

Wang et al.

Yes

Yes

Yes

Yes

Yes

Yes

Yes

Yes

No

No

Yes

81%

Low

  1. Q1. Were the two groups similar and recruited from the same population?
  2. Q2. Were the exposures measured similarly to assign people to both exposed and unexposed groups?
  3. Q3. Was the exposure measured in a valid and reliable way?
  4. Q4. Were confounding factors identified?
  5. Q5. Were strategies to deal with confounding factors stated?
  6. Q6. Were the groups/participants free of the outcome at the start of the study (or at the moment of exposure)?
  7. Q7. Were the outcomes measured in a valid and reliable way?
  8. Q8. Was the follow-up time reported and sufficient to be long enough for outcomes to occur?
  9. Q9. Was follow-up complete, and if not, were the reasons for loss to follow-up described and explored?
  10. Q10. Were strategies to address incomplete follow-up utilized?
  11. Q11. Was appropriate statistical analysis used?