Table 1 Patient and tumour characteristics at initial management

Age at diagnosis

< 50 years, n (%)

≥ 50 years, n (%)

Median (years)

102 (25%)

305 (75%)

58

13 (62%)

8 (38%)

48

Tumour site, n (%)

Temporal

Frontal

Parietal

Occipital

Thalamic

Other

136 (33%)

113 (28%)

97 (24%)

34 (8%)

19 (5%)

8 (2%)

13 (62%)

2 (9.5%)

1 (5%)

2 (9.5%)

3 (14%)

0 (0%)

Extent of resection, n (%)

Near-Total

Subtotal

Biopsy

177 (43%)

171 (42%)

59 (15%)

12 (57%)

7 (33%)

2 (10%)

Ki67 index, n (%)

< 30%

≥ 30%

Unknown

Median

147 (36%)

219 (54%)

41 (10%)

30

5 (24%)

13 (62%)

3 (14%)

45

IDH1 mutation, n (%)

Yes

No

18 (4%)

389 (96%)

2 (10%)

19 (90%)

MGMT methylation, n (%)

No

Yes

Unknown

123 (30%)

102 (25%)

182 (45%)

12 (57%)

0

9 (43%)

ECOG performance status at baseline, n (%)

0

1

2

3,4

118 (29%)

172 (42%)

87 (21%)

30 (7%)

11 (52%)

7 (33%)

2 (10%)

1 (5%)