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Table 2 Clinical factors associated with spinal leptomeningeal relapse analysed using chi-square test of independence

From: Leptomeningeal neuraxis relapse in glioblastoma is an uncommon but not rare event associated with poor outcome

 

p-value:

Age at initial diagnosis

 

<50 vs. ≥ 50 years old

p < 0.01

Initial tumour site

 

Temporal lobe vs. other locations

p < 0.01

Ki67

 

< 30% vs. ≥ 30%

p = 0.38

Extent of Surgery

 

Near-Total vs. Subtotal vs. Biopsy

p = 0.42

MGMT

 

Unmethylated vs. Methylated

p < 0.01

ECOG

 

0,1 vs. 2,3,4

p = 0. 21

  1. MGMT: O6-methylguanine-DNA methyltransferase, ECOG: Eastern Cooperative Oncology Group