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Table 3 Multiple logistic regression analyses showing that high risk for significant OSA based on the mNOSAS score was selected by the model with a 14 times risk of developing a severe COVID-19 AE (A), and that the age at admission, the mNOSAS score, reduced dyspnea sensation at admission and the severity of COVID-19 AE were associated with the risk of developing severe disability at discharge (mRS score ≥ 3)

From: Obstructive sleep apnea: a major risk factor for COVID-19 encephalopathy?

A

Severe COVID-19 AE

Odds ratio

p value

[95% Confident Interval]

Modified NOSAS score

14.52

 < 0.001

4.37

48.22

B

mRS

Odds ratio

p value

[95% Confident Interval]

Age at admission

1.07

0.018

1.01

1.13

Modified NOSAS score

1.17

0.058

0.99

1.38

Reduced dyspnea at admission

0.28

0.017

0.10

0.79

Severe COVID-19 AE

7.37

0.004

1.87

29.02

  1. Abbreviations: COVID-19 AE COVID-19 acute encephalopathy, OSA Obstructive sleep apnea, mRS modified Rankin Scale