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Table 1 Sample sociodemographic and health characteristics

From: Exploring humanistic burden of fatigue in adults with multiple sclerosis: an analysis of US National Health and Wellness Survey data

  

Matched

Non-MS Controls

RRMS

p Value

RRMS+LF

(MFIS-5 = 0-14)

RRMS+HF

(MFIS-5 = 15+)

p Value

  

(N=1,494)

(N=498)

(N=375)

(N=123)

  

Mean/n

SD/%

Mean/n

SD/%

Mean/n

SD/%

Mean/n

SD/%

Age (years)

50.98

13.08

50.52

12.80

0.500

51.12

12.80

48.71

12.67

0.070

Sex

Male

367

24.56

126

25.30

0.787

94

25.07

32

26.02

0.928

Female

1,127

75.44

372

74.70

281

74.93

91

73.98

Race

White

1,217

81.46

406

81.53

0.999

301

80.27

105

85.37

0.385

Black/African American

221

14.79

74

14.86

59

15.73

15

12.20

Asian

18

1.20

6

1.20

4

1.07

2

1.63

Some other race or origin

38

2.54

12

2.41

11

2.93

1

0.81

Marital Status (% yes)

Married/living with a partner

911

60.98

312

62.65

0.686

242

64.53

70

56.91

0.129

Education (% yes)

University degree

698

46.72

222

44.58

0.436

169

45.07

53

43.09

0.781

Employment Status

Employed full time

670

44.85

137

27.51

<0.001

115

30.67

22

17.89

<0.001

Self-employed

95

6.36

16

3.21

12

3.20

4

3.25

Employed part time

126

8.43

28

5.62

23

6.13

5

4.07

Homemaker

120

8.03

54

10.84

43

11.47

11

8.94

Retired

279

18.67

124

24.90

101

26.93

23

18.70

Student

19

1.27

7

1.41

4

1.07

3

2.44

Long-term disability

91

6.09

100

20.08

53

14.13

47

38.21

Not employed, but looking for work

71

4.75

19

3.82

15

4.00

4

3.25

Not employed and not looking for work

23

1.54

13

2.61

9

2.40

4

3.25

Annual Household Income

<$50,000

564

37.75

241

48.39

<0.001

164

43.73

77

62.60

0.001

$50,000 to $74,999

284

19.01

82

16.47

63

16.80

19

15.45

≥$75,000

582

38.96

160

32.13

134

35.73

26

21.14

Decline to answer

64

4.28

15

3.01

14

3.73

1

0.81

Insurance Typea

Commercially insured

928

64.04

239

49.08

<0.001

190

51.77

49

40.83

0.090

Medicaid

132

9.11

43

8.83

29

7.90

14

11.67

Medicare

281

19.39

181

37.17

129

35.15

52

43.33

Other type of insurance (VA/CHAMPUS, TRICARE, not sure)

45

3.11

17

3.49

15

4.09

2

1.67

Not insured

63

4.35

7

1.44

4

1.09

3

2.50

Charlson Comorbidity Index Score

0.68

1.80

0.79

2.63

0.304

0.66

2.85

1.16

1.79

0.067

Body Mass Index (kg/m2)

29.27

7.50

28.97

7.79

0.452

28.76

7.41

29.63

8.86

0.288

Smoking Status (% yes)

Current smoker

254

17.00

101

20.28

0.098

68

18.13

33

26.83

0.037

Alcohol Use (% yes)

Drinks alcohol

1006

67.34

311

62.45

0.052

238

63.47

73

59.35

0.477

Days Exercising in Past Month

7.71

8.80

6.7

8.95

0.027

7.41

9.24

4.54

7.64

0.002

MFIS-5 Score among RRMS

NA

NA

10.56

4.97

NA

8.50

3.84

16.82

1.71

<0.001

  1. For the set of tests shown in the table, the corrected alpha levels were 0.012 and 0.014 for comparisons between RRMS and controls and between RRMS+LF and RRMS+HF, respectively. The differences between RRMS+LF and RRMS+HF in smoking status (p=0.037 > p=0.014) and differences between RRMS and controls in days exercised in the past month (p=0.027 > p=0.012) were no longer statistically significant
  2. CHAMPUS Civilian Health and Medical Program of the Uniformed Services, HF high fatigue, LF low fatigue, MFIS-5 5-item Modified Fatigue Impact Scale, MS multiple sclerosis, NA not applicable, RRMS relapsing-remitting multiple sclerosis, SD standard deviation, VA Veterans Affairs
  3. aPercent values were calculated using non missing data: non-MS matched controls, n=1,449; RRMS, n=487; RRMS+LF, n=367; RRMS+HF, n=120
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BMC Neurology

ISSN: 1471-2377

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