Table 2 Meta-analysis study characteristics
Citation | Target Condition | Sample Size (Diseased/ Healthy) | Assessment Method (Visual/Quantitative) | Sensitivity (FDG-PET/ASL-MRI) | Specificity (FDG-PET/ASL-MRI) | Positive predictive value (FDG-PET/ASL-MRI) | Negative predictive value (FDG-PET/ASL-MRI) |
|---|---|---|---|---|---|---|---|
Anazodo et al. [2017]Â [27] | Frontotemporal dementia (FTD) | 10/10 | Visual | 0.88/0.66 | 0.90/0.62 | 0.90/0.63 | 0.88/0.65 |
Ceccarini et al. [2020]Â [19] | Different types of dementia | 27/30 | Visual | 0.93/0.64 | 0.70/0.71 | 0.73/0.66 | 0.91/0.68 |
Quantitative | 0.79/0.57 | 0.63/0.81 | 0.65/0.72 | 0.76/0.67 | |||
Fällmar et al. [2017] [20] | Frontotemporal dementia (FTD) | 20/38 | Visual | 0.96/0.53 | 0.54/0.84 | 0.71/0.80 | 0.91/0.60 |
Alzheimer’s disease (AD) | 25/38 | ||||||
Musiek et al. [2012] [31] | Alzheimer’s disease (AD) | 15/19 (qualitative assessment) | Visual | 0.66/0.63 | 0.97/0.92 | 0.95/0.86 | 0.78/0.76 |
13/18 (quantitative assessment) | Quantitative | 0.72/0.77 | 0.92/0.92 | 0.87/0.87 | 0.82/0.85 | ||
Tosun & Jagust et al. [2016]Â [34] | Early mild cognitive impairment (early-MCI) | 30/34 | Quantitative | 0.90/0.83 | 0.88/0.84 | 0.86/0.82 | 0.90/0.84 |
Late mild cognitive impairment (late-MCI) | 25/34 | 0.87/0.74 | 0.88/0.74 | 0.84/0.67 | 0.90/0.79 | ||
Alzheimer’s disease (AD) | 20/34 | 0.95/0.80 | 0.94/0.88 | 0.90/0.79 | 0.96/0.88 | ||
Tosun & Rabinovici et al. [2016]Â [35] | Behavioral variant of frontotemporal dementia (bvFTD) | 32/15 | Quantitative | 0.79/0.78 | 1.00/0.92 | 1.00/0.96 | 0.62/0.59 |
Alzheimer’s disease (AD) | 28/15 | 0.78/0.86 | 1.00/0.92 | 1.00/0.95 | 0.70/0.77 |