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Table 1 Demographic characteristics and history of the disease-FAS population

From: High-dose pharmaceutical-grade biotin in patients with demyelinating neuropathies: a phase 2b open label, uncontrolled, pilot study

Group

CIDP

anti-MAG

CMT1

All

Participants (n)

5

5

5

15

Men (n)

2 (40%)

3 (60%)

2 (40%)

7 (47%)

Women (n)

3 (60%)

2 (40%)

3 (60%)

8 (53%)

Age (years)

66 ± 15; 63 (61;79)

69 ± 8; 65 (63;72)

49 ± 11; 52 (49;55)

61 ± 14; 62 (52;72)

Time since first appearance of symptoms (years)

18 ± 9; 14 (13;15)

11 ± 11; 5 (3;17)

11 ± 16; 5 (3;6)

13 ± 12; 12 (3;17)

Patients with progression (n)

2

2

4

8

Time since progression (years)

2.7 ± 1.5; 1.2 (1.0;1.3)

1.9 ± 1.4; 1.9 (0.7;3.0)

1.6 ± 1.4; 1.4 (0.6;2.5)

1.7 ± 1.3; 1.3 (1.0;2.4)

  1. Age, time since first appearance of symptoms and time since progression are expressed as mean ± SD; median (IQR). If the day and the month of date of the first appearance of symptoms/date of progression were missing, it was estimated by the 15th of June, if only the day was missing, the day was estimated by the 15th of the corresponding month