Table 4 Clinical scores. Secondary endpoints
W0 | W12 | W24 | W36 | W48 | Absolute change between W0 and W48 | p-value | |
|---|---|---|---|---|---|---|---|
MRC | 168 (160;177) | 175 (164;178) | 176 (166;179) | 178 (164;180) | 176 (166;180) | 3 (0; 9) | .037 |
INCAT | 6 (4;8) | 5 (2;10) | 4 (2;7) | 4 (2;7) | 3 (1;7) | -3 (-3; 0) | .014 |
Timed 10-m walk (s) | 8 (7;12) | 7 (6;9) | 8 (7;10) | 8 (6;12) | 7 (6;12) | -1 (-2; 0) | .178 |
6-min walking distance (m) | 375 (293;474) | 419 (315;470) | 442 (293;489) | 427 (285;489) | 469 (278;506) | 69 (10;104) | < .001 |
ONLS | 3 (2;4) | 2 (2;3) | 3 (2;3) | 3 (2;4) | 2 (1;4) | -1 (-1;1) | .264 |