Table 1 Reported cases of pregnancy-associated brain abscess in the medical literature
From: Actinomyces meyeri-induced brain abscess in pregnancy: a case report
author/year | Age(year)/gestational age | preliminary sympt om and sign | Location of brain abscess | source of infecti on | culture | Types of antibiotics | Surgical treatment | Maternal and infant outcome |
|---|---|---|---|---|---|---|---|---|
Raskind R/1966 | 24/28 W | HA, speech dysfunction, left foot weakness | Frontal lobe | - | Anaerobic β Streptococcus | Tetracycline,procaine penicillin | Abscess aspiration by craniotomy | minimal residual right cranial nerve weakness at 11 months follow-up/good(Vaginal delivery) |
Brahan J/1967 | ND | HA, confusion | R temporal | R mastoiditis | ND | Surgical drainage | ND | ND |
Kahn HS/1975 | 31/ND | Dysphagia, R-sided weakness | L cerebral hemisphere | IUD (safe T-coil), incomplete abortion | Enterobacter cloacae | None | None | Death/First-trimester spontaneous abortion |
Martinez AJ/1980 | 26/ND | Fever, HA,seizures, L hemiplegia, coma | R frontotemporal,occipital lobes | Corticosteroids | Acanthamoeba culbertson | ND | ND | Death/ND |
Wolf P/1983 | 17/37 W | HA, nausea, vomiting | R frontal lobe | - | Pseudomonas species (contaminant) | ampicillin IV | ND | Death/Normal infant (term cesarean) |
Opsahl MS/1983 | 33/29 W | HA, fever, myalgia, confusion, nuchal rigidity | L parieto-occipital lobe | Sarcoidosis | Nocardia species | ND | surgical drainage by craniotomy | Alive and well/Preterm Birth(Low forceps delivery) |
Braun TI/ 1991 | 25/16w | L-sided HA, mildly confusion, R-sided neurologic signs | L occipital lobe | None | Nocardia asteroids | Sulfisozazole, ampicillin, ceftriaxone | Left occipital craniotomy | Good recovery/Preterm birth,good(Caesarian section) |
Cihangiroglu M/2001 | 25/25 W | R sixth cranial nerve palsy | R cerebral hemisphere (multiple) | Infectious cerebral vasculitis | Aerobic and anaerobic organisms, including Peptostreptococcus | ND | Craniotomy and decompression | ND/ND |
Baxi LV/ 2001 | 36/10w | R hemiparesis, aphasia, DIC | L basal ganglion | Thromphilia | Propienobacterium acnes, staphylococcus capitis | Cefotaxime, ceftazine, vancomycin | None | Residual hemiparesis amenorrhea/good(Low forceps delivery) |
Wax JR/ 2004 | ND/ 36 W | HA confusion seizure | L temporal lobe | Sinusitis | negative | Cefepime, vancomycin, metronidazole | None | Good recovery/good(cesarean delivery) |
Liu SSH/ 2004 | 32/35w | stuffy nose, rhinorrhea, HA, bilater al eyebal l soreness and low-grade fever | L frontal lobe | Sinusitis | β-hemolytic streptococcus | metronidazole, penicillin G sodium, gentamycin, metronidazole | Drainage | Hydrocephalus hemiparesis, diabetes inspidus/Good(Caesarian section) |
Kim HC/ 2007 | 38/30 W | HA, sinus infecti on, meningeal sign, sudden deterioration of (VA) AT 34 W | Pituitary | Sinusitis | Streptococcus viridians | ceftriaxone,amikacin | Transphenoidal microsurgic al removal | Good recovery/LBW(Emergency Caesarian section) |
Jacob CE/ 2009 | 23/35w | hronic otitis media, fever, HA, gait ataxia | L cerebellar hemisphere | Otitis | Pseudomonas aeruginosa | Penicillin, ciprofloxacin, TMP/SMX | Partial excision of the abscess, modified radical mastoidectomy | Dry left ear, with no residual hearing/good(Caesarian section) |
Salvi N /2010 | 19/39w | Severe HA, facial swelling,mental status | frontal subdural empyema | ND | ND | ND | A right frontal craniotomy with evacuation of empyema | ND/ND(Emergency Caesarian section) |
Hobson DT /2011 | 35/21w | HA, facial swelli ng, mental status changes | L fronta l, tempo Ral, parietal lobe | Infected tooth | Bacteroides fragilis, Wolinella species, Campylobac ter gracilis, Prevotella buccae | Ampicillin, cefotaxime, metronidazole | Drainage, lobectomy | Broca’s aphasia and apraxia with right hemiplegia/good(ce sarean delivery) |
Yoshida M/ 2013 | 24/22w | - | R frontal lobe | none | MSSA | Cefotaxime, meropenem, amoxicillin | None | Good recover/Good(Vaginal delivery) |
Bulthuis VJ/2015 | 36/- | HA, nausea, vomiting | brain stem absces | recurring skin abscesses | Streptococcus constellatus | ceftriaxone, metronidazol e, and fluoxetine) for 12 weeks. | acute stereotactic aspiration of a brainstem abscess | favorable outcome/spontaneou s abortion |
Jendoubi A/2016 | 23/32w | HA, blurry vision and epigastric pain, generalized tonic-clonic seizures | R parieto- occipital lobe juncti on | None | negative | cefotaxime metronidazole,fosfomycin | stereotactic aspiration of the abscess | Epilepsy, homonymous hemianopia/Preterm birth,good(Emergency Caesarian section) |
Bahrami R/20 17 | 25/28w | HA, nausea and vomiting, sudden loss of consciousne ss. | R frontal | sinusitis | negative, but smear was gram positive cocci | ND | emergency large decompres sive craniotomy | died after surgery/died because of preterm delivery(Caesarian section) |
our case | 35/8w | Fever with vomiti ng, sudden loss of consciousness | R tempo Ral,parietal lobe | none | Actinomyces meyeri | Vancomycin, meropenem, ornidazole | Craniotomy, Drainag e | Vegetative state/Induce labor |