From: Actinomyces meyeri-induced brain abscess in pregnancy: a case report
author/year | Age(year)/sex | preliminary symptom and sign | Location of brain abscess | source of infection | Other cultured organisms | antibiotic | Surgical treatment | outcome |
---|---|---|---|---|---|---|---|---|
Dijkmans BA/1984 | 28/F | HA, fever, AMS, meningismus, R-sided hemiparesis | L parietal lobe brain abscess, ventriculitis | Unknown | Streptobacillus moniliformis | Benzathine penicillin 24 mill U x 1 m then 36 mill U + dexamethasone x 1 m | Burr hole drainage, recurrent percutaneous punctures for external drainage | No recurrence at 1 year |
Kuijper EJ/1992 | 44/M | 1 month R-sided weakness and dysarthria | L fronto-parietal lobe abscesses (x2), R occi pital lobe absc ess | Unknown | Actinobacillus actinomycentemcomitans | Amoxicillin 6 w, amoxicillin x 12 m | Stereotactic brain biopsy and drainage | Clinical cure; follow-up period not specified |
Park HJ/2014 | 46/M | 3d HA and aphasia | L lung mass, L fronto-parietal lobe brain abscess | Unknown | propionibacterium acnes, Fusobacterium nucleatum | penicillin 4 mill Ux 4 w, metronidazole x 4 w, amoxicillin x 11 m | Stereotactic brain biopsy | Resolution of symptoms and significant reduction in mass size at 5 m |
Fernandez-Valle T/2014 | 57/M | Hours AMS and new onset seizure | L parietal lobe abscess | Dental procedure week prior | not reported | Ceftriaxone and metronidazole x unknown duration, amoxicillin x 12 m | Stereotactic brain biopsy | No recurrence at 1 year |
Clancy U/2015 | 55/F | 2d HA, R hemisensory loss, unsteady gait | L parietal lobe brain abscess | Dental extraction 7d prior | Group B streptococcus, Staphilococcus capitis | Vancomycin x 11 d, metronidazole x 1 m, Ceftriaxone x 4 m, amoxicillin x 6 m | Craniotomy and drainage | No recurrence at 4 m |
Rolfe R/2016 | 50/M | Unknown | Brain abscess | Pneumonitis | Actinobacillus, mixed anaerobic flora | Ceftriaxone x 1 m, penicillin x5 m | Brain biopsy | Lost to follow-up |
Rolfe R/ 2016 | 44/M | Unknown | frontal brain abscess | Sinusitis | Microaerophilic streptococcus, Strep mitis B | Ceftriaxone x 1 m | Brain biopsy and drainage | Lost to follow-up |
Rahiminejad M/2015 | 50/M | Dysphasia,R-sided facial weakness | L temporal lobe | unable to identify.but periodontal disease | Actinomyces meyeri and Fusobacterium nucleatum. | metronidazole and clindamycin 1 m, Subsequent unclear | twice stereotactic aspiration | abscess recurred after 1 m |
Sah R/2020 | 35/M | HA, L-si ded weakness | R parietal parasa gittal region | dental hygiene | Actinomyces meyeri. | Ampicillin-sulbactam iv 6w and oral 12 m | craniotomy and lesion was excised | No recurrence at 1 year |
Shintaku M/2020 | 72/M | Fever,L-sided hemiparesis | R parietal lobe | Long-term corticosteroid and an immuno- suppressive drug (mizoribine) | a small number of sulfur granules | vancomycin and meropenem iv 3d | none | died of respiratory insufficiency 2 days after admission |
Pereira AJDSPR/2022 | 60/M | HA,barely perceptible speech,L-sided hemiparesis | R posterior parietal cortico-subcortical | dental origin | Actinomyces meyeri and Fusobacterium nucleatum | penicillin and metronidazole iv 3w and orally thereafter | surgical drainage | residual neurological deficits |
Our case | 39/F | Fever with vomiti Ng,AMS | R tempo ral and parietal lobe | none | none | Vancomycin, meropenem, Ornidazole x3 m | craniotomy, Drainag e | Vegetative state |