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Table 1 Baseline Characteristics of Patients Based on Atrial Fibrillation

From: Short- and long-term outcomes of patients with minor stroke and nonvalvular atrial fibrillation

Variables

Total

NVAF

Non-AF

P value

(n = 4753 [100%])

(n = 222 [4.7%])

(n = 4531 [95.3%])

Age, y

61.9 ± 11.1

71.1 ± 8.9

61.4 ± 11.0

< 0.001

Female

1413 (29.7)

69 (31.1)

1344 (29.7)

0.65

Medical history

    

 Current smoking

1563 (32.9)

43 (19.4)

1520 (33.5)

< 0.001

 Hypertension

3005 (63.2)

138 (62.2)

2867 (63.3)

0.74

 Diabetes mellitus

1114 (23.4)

41 (18.5)

1073 (23.7)

0.07

 Dyslipidemia

381 (8.0)

19 (8.6)

362 (8.0)

0.76

 Prior CAD

509 (10.7)

65 (29.3)

444 (9.8)

< 0.001

 Heart failure

23 (0.5)

8 (3.6)

15 (0.3)

< 0.001

 Prior Stroke/TIA

1073 (22.6)

49 (22.1)

1024 (22.6)

0.85

 PVD

40 (0.8)

2 (0.9)

38 (0.8)

0.92

 BMI

24.7 (22.9–26.7)

24.2 (22.0-26.4)

24.7 (22.9–26.7)

0.06

Baseline NIHSS

2.0 (1.0–4.0)

2.0 (1.0–4.0)

2.0 (1.0–4.0)

0.37

 0

591 (12.4)

28 (12.6)

563 (12.4)

 

 1

965 (20.3)

35 (15.8)

930 (20.5)

 

 2

1038 (21.8)

58 (26.1)

980 (21.6)

 

 3

851 (17.9)

31 (14.0)

820 (18.1)

 

 4

774 (16.3)

44 (19.8)

730 (16.1)

 

 5

534 (11.2)

26 (11.7)

508 (11.2)

 

CHA2DS2-VASc

2.0 (1.0–3.0)

3.0 (2.0–4.0)

2.0 (1.0–3.0)

< 0.001

Time measure

    

 Onset to door, hours

5.9 (2.4–12.4)

3.7 (1.6–7.2)

6.0 (2.5–12.6)

< 0.001

  ≤3 h

1513 (31.8)

97 (43.7)

1416 (31.3)

 

  3-4.5 h

503 (10.6)

33 (14.9)

470 (10.4)

 

  >4.5 h

2737 (57.6)

92 (41.4)

2645 (58.4)

 

 Length of stay

12.0 (10.0–15.0)

13.0 (10.0–15.0)

12.0 (10.0–14.0)

0.10

Laboratory

    

 Baseline blood glucose, mmol/L

5.5 (4.9-7.0)

5.5 (4.9–6.5)

5.5 (4.9-7.0)

0.21

 Serum creatinine, µmol/L

69.0 (58.0–81.0)

75.8 (63.3–92.0)

69.0 (58.0–80.0)

< 0.001

 Serum ALT, U/L

18.0 (13.0–25.0)

17.0 (13.0–25.0)

18.0 (13.0–25.0)

0.24

SBP at admission, mmHg

150.0 (136.5–165.0)

147.0 (134.0-164.0)

150.0 (137.0-165.0)

0.001

DBP at admission, mmHg

87.0 (80.0–96.0)

83.5 (77.0–91.0)

87.0 (80.0-96.5)

< 0.001

Medication history

    

 Antiplatelet

823 (17.3)

76 (34.2)

747 (16.5)

< 0.001

 Anticoagulant

29 (0.6)

15 (6.8)

14 (0.3)

< 0.001

In-hospital treatment

    

 Thrombolysis

647 (13.6)

38 (17.1)

609 (13.4)

0.12

 EVT

8 (0.2)

1 (0.5)

7 (0.2)

0.29

 Antiplatelet

4640 (97.6)

192 (86.5)

4448 (98.2)

< 0.001

 Anticoagulant

402 (8.5)

104 (46.8)

298 (6.6)

< 0.001

  Warfarin

74 (1.6)

60 (27.0)

14 (0.3)

< 0.001

  DOACs

    

   Rivaroxaban

4 (0.1)

2 (0.9)

2 (0.0)

< 0.001

   Dabigatran

16 (0.3)

14 (6.3)

2 (0.0)

< 0.001

 Antihypertensive agents

2251 (47.4)

106 (47.7)

2145 (47.3)

0.91

 Lipid-lowering agents

4577 (96.3)

213 (95.9)

4364 (96.3)

0.78

 Glucose-lowering agents

1202 (25.3)

38 (17.1)

1164 (25.7)

0.004

  1. NVAF indicates nonvalvular atrial fibrillation; CAD, coronary artery disease; TIA, transient ischemic attack; PVD, peripheral vascular disease; BMI, body mass index; NIHSS, National Institutes of Health Stroke Scale; CHA2DS2-VASc, congestive heart failure, hypertension, age ≥ 75 years, diabetes, stroke/transient ischemic attack/thromboembolism, vascular disease, age 65 to 74 years, and sex category; ALT, alanine aminotransferase; SBP, systolic blood pressure; DBP, diastolic blood pressure; EVT, endovascular treatment; DOAC, direct oral anticoagulant