Table 6 Top most significantly altered IPA canonical pathways
| Â | p-value | z-score |
|---|---|---|
1. Phagosome Formation | 1.27 × 10–8 | -4.03 |
2. Neuroinflammation Signaling Pathway | 1.02 × 10–7 | -2.89 |
3. CREB Signaling in Neurons | 1.29 × 10–6 | -2.84 |
4. Fcγ Receptor-mediated Phagocytosis in Macrophages and Monocytes | 2.15 × 10–6 | -2.65 |
5. Autophagy | 6.17 × 10–5 | -2.65 |
6. Production of Nitric Oxide and Reactive Oxygen Species in Macrophages | 3.47 × 10–5 | -2.12 |
7. fMLP Signaling in Neutrophils | 1.95 × 10–5 | -2.00 |
8. Role of Pattern Recognition Receptors in Recognition of Bacteria and Viruses | 5.89 × 10–5 | -2.45 |
9. CXCR4 Signaling | 9.12. × 10–5 | -2.24 |
10. TREM1 Signaling | 1.26 × 10–4 | -2.24 |
11. IL-8 Signaling | 1.10 × 10–4 | -2.45 |