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Fig. 3 | BMC Neurology

Fig. 3

From: Adjunctive tonic motor activation enables opioid reduction for refractory restless legs syndrome: a prospective, open-label, single-arm clinical trial

Fig. 3

Relationship between acute TOMAC response and opioid dose reduction A Relationship between maximum successful daily MME reduction from baseline, expressed as percentage of baseline dose (y-axis) and PGI-I score of RLS symptom reduction during 30-min TOMAC sessions, assessed at the end of step-down 1 (x-axis). Each point represents one participant. Dashed line indicates linear regression. B Same as A, except PGI-I score represents RLS symptom reduction during the 30-min after the 30-min TOMAC sessions. Abbreviations: MME, morphine milligram equivalent; PGI-I, patient global impression of improvement; TOMAC, tonic motor activation

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BMC Neurology

ISSN: 1471-2377

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