Table 3 Details of sequences acquired on the Siemens Prisma 3T MRI
MP2RAGE | Multi-delay 3D GRASE PCASL | IR-IVIM | |
|---|---|---|---|
Voxel resolution (mm3) | 1 × 1 × 1 | 3.5 × 3.5 × 4.5 | 2.4 × 2.4 × 2.4 |
Matrix size | 224 × 216 × 176 | 64 × 56 × 32 | 88 × 88 × 45 |
FoV (read x PE) (mm) | 224 × 216 | 224 × 196 | 210 × 210 |
Slice coverage (mm) | 176 | 144 | 130 (20% slice gap) |
Orientation | Sagittal | Transverse | Transverse |
PE direction | A ≫ P | R ≫ L | P ≫ A |
TE (ms) | 2.59 | 13.44 | 72 |
TR (ms) | 4000 | PLD + 2200 | 10,700 |
Flip angle (°) | 4, 5 | 90 (excitation), 160 (refocusing) | 90 (excitation), 180 (refocusing) |
Acquisition bandwidth (Hz/pix) | 220 | 2298 | 2030 |
Parallel imaging | × 3 | None | × 2 |
Total scan time | 5 min 38 s | 6 min 16 s | 4 min 09 s |
Other sequence-specific parameters | TI1 = 600 ms | LD = 1800 ms | Slice-sel. IR EPI with TI = 1800 ms |
TI2 = 1800 ms | PLD = 400, 800, 1200, 1600, 1800, 2000, 2200, 2400, 2800 | Single direction DWI (DW along PE) with b values: 0, 10, 20, 30, 40, 50, 60, 100, 200, 300, 400, 500, 600, 800, 1000 s/mm2 | |
PE partial Fourier 7/8 | Additional M0 scan, with blip-reversed PE for distortion correction | b = 0 volume acquired with blip-reversed PE for distortion correction | |
Background suppression | |||
4 segments (in PE direction) | |||
Slice partial Fourier 6/8 | |||
PCASL labelling plane positioned using sagittal and coronal neck ToF MRA |