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Table 4 Incidental findings from cardiac assessments

From: Updating the study protocol: Insight 46 – a longitudinal neuroscience sub-study of the MRC National Survey of Health and Development – phases 2 and 3

12-Lead Electrocardiogram (ECG) and Heart Rate Variability Recording (HRV)

• ST-segment abnormalities,

• T-wave abnormalities,

• Left ventricular hypertrophy,

• Left-axis deviation,

• Sinus arrhythmia,

• Atrial fibrillation/fluttera,

• Isolated supraventricular/ventricular ectopics,

• Bi/trigemini,

• Non-sustained ventricular tachycardia or other malignant ventricular arrhythmiasa,

• Bundle branch block,

• Prolonged PR interval,

• 2nd degree AV block or highera

Echocardiogram

• Valve prosthesis,

• Mild valve stenosis,

• Moderate to severe valve stenosisa,

• Mild valvular regurgitation,

• Moderate to severe valvular regurgitationa,

• Impaired LV or RV systolic functiona,

• Severe LV diastolic dysfunctiona,

• Chamber enlargement (e.g., left atrial dilatation, right ventricular dilatation, etc.),

• Left or right ventricular hypertrophy LV outflow tract obstruction,

• Regional wall motion abnormalitya,

• Intracardiac shunta,

• Pericardial effusiona,

• Pulmonary hypertension,

• Mass lesion (vegetation, thrombus, or tumour)a,

• Myocardial infiltration (suggesting cardiac amyloidosis)a,

• Presence of congenital heart disease,

• Aortic dilation, aortic coarctationa, or aortic dissectiona

Carotid intima-media thickness (cIMT)

• Carotid artery stenosis (≥ 50% diameter),

• Carotid atheromatous plaques,

• Carotid artery thrombus,

• Carotid tumoursa,

• Carotid dissectiona,

• Large thyroid mass (> 1 cm)a,

• Lymphadenopathy

  1. aIndicates a potentially urgent finding, particularly if not previously known about