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Table 3 Features that discriminate Pre-tremor condition from Tremor and Control conditions (multiple comparisons corrected p-value < 0.01)

From: Parkinson’s disease tremor prediction using EEG data analysis-A preliminary and feasibility study

Condition

Feature

EEG frequency band

EEG channel

Description

Off-medication, eyes-closed

Form factor

Delta

F7, FC5, FC1, PZ, O1, P4, P8, CP6, CP2, C4, CP3, P1, P5, PO3, POZ, PO8, P2, CP4, TP8, FT8

The feature value for pre-tremor is significantly higher compared with tremor and control conditions (p < 0.01) in 3-s window.

Peak frequency

Gamma

FC6

ON-medication, eyes-closed

Form factor

Delta

F4, P4

Significantly larger value for 3-s pre-tremor segment compared with the same duration of tremor and control conditions (p < 0.01).

Alpha

C3, CP5, CP1, CP2, CP3

HOS5

Gamma

F3

Skewness

Gamma

F3

Kurtosis

Gamma

FC2, FT7, FCZ

HOS6

Gamma

FC5, FC6, FC2, FT7, FCZ

L-skewness

Gamma

F7

L-kurtosis

Gamma

C4, FT10

ON-medication, eyes-open

Form factor

Theta

C2

Significantly larger value for 3-s pre-tremor segment compared with the same duration of tremor and control conditions (p < 0.01).

Alpha

CP2

HOS5

Gamma

FZ, F3, F5

HOS6

Gamma

FC5, FC6, FC2, F1, FC3, FT7, FCZ

Kurtosis

Gamma

FC6, FC3, FT7, P1

Skewness

Gamma

F3, F5

OFF-medication, eyes-open

Form factor

Delta

FZ, F3, F7, FC5, C3, TP9, CP5, CP1, PZ, P3, O1, O2, P4, P8, CP6, CP2, CZ, C4, FC2, F1, TP7, P1, P5, PO3, POZ, PO4, PO8, P6, P2, CP4, TP8, C6, C2, F2, AF4

Features for pre-tremor value are significantly larger compared with tremor and control conditions (p < 0.01) in 3-s window.