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Table 4 Factors related to six-month poor prognosis after acute intracerebral hemorrhage

From: Significance of serum sestrin2 as a biomarker of severity and functional outcome in acute intracerebral hemorrhage: a prospective observational longitudinal study

Variables

mRS 3–6

mRS 0–2

P value

Number

58

68

 

Age (years)

62.1 ± 9.8

61.7 ± 10.6

0.822

Gender (male/female)

28/30

41/27

0.177

Body mass index (kg/m2)

24.1 ± 3.1

24.3 ± 3.6

0.792

Hypertension

37 (63.8%)

38 (55.9%)

0.367

Diabetes mellitus

14 (24.1%)

17 (25.0%)

0.911

Hyperlipidemia

19 (32.8%)

21 (30.9%)

0.822

Coronary heart disease

7 (12.1%)

3 (4.4%)

0.113

Cigarette smoking

18 (31.0%)

29 (42.7%)

0.179

Alcohol drinking

19 (32.8%)

30 (44.1%)

0.192

Statin use

16 (27.6%)

17 (25.0%)

0.742

Anticoagulant use

3 (5.2%)

4 (5.9%)

0.862

Antiplatelet use

6 (10.3%)

12 (17.7%)

0.243

Antihypertensive use

32 (55.2%)

35 (51.5%)

0.678

Hypoglycemic use

12 (20.7%)

13 (19.1%)

0.825

Admission time (h)

9.2 (6.8–12.4)

8.9 (4.8–14.7)

0.862

Sampling time (h)

10.9 (8.3–14.6)

10.4 (6.5–16.4)

0.818

Systolic arterial pressure (mmHg)

140.3 ± 23.2

145.1 ± 22.8

0.243

Diastolic arterial pressure (mmHg)

85.3 ± 10.0

86.1 ± 9.6

0.638

Hemorrhage locations (lobar/deep)

17/41

16/52

0.462

Intraventricular hemorrhage

20 (34.5%)

11 (16.2%)

0.017

Subarachnoidal hemorrhage

9 (15.5%)

2 (2.9%)

0.013

NIHSS scores

11 (11–13)

8 (4–10)

< 0.001

Hematoma volume (ml)

21 (13–28)

9 (6–15)

< 0.001

Blood leucocyte count (×109/l)

8.3 (6.2–10.9)

7.9 (6.3–9.4)

0.829

Blood glucose levels (mmol/l)

12.9 (9.5–17.1)

10.8 (9.2–12.3)

0.014

Serum sestrin2 levels (ng/ml)

13.7 (4.7–23.0)

3.6 (2.4–7.3)

< 0.001

  1. Data were summarized in form of number (proportion), mean ± standard deviation or median (upper-lower quartile) based on datum patterns. The Chi-square test, Fisher exact test, Student’s 𝑡-test and Mann-Whitney test were employed for statistical analysis
  2. NIHSS denotes National Institutes of Health Stroke Scale, mRS modified Rankin Scale