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Table 2 Comparison between cases with good and poor clinical outcomes of RIVT

From: Repeated intravenous thrombolysis in recurrent ischemic stroke within 3 months: a systematic review

Influencing factors

Good-outcome group (18 cases)

Poor-outcome group (6 cases)

P value

Male [cases (%)]

11 (61.11%)

3 (50.00%)

0.494

Age (year) [median (min, max)]

69.25 (42, 87)

78.00 (51, 83)

0.156

ACC involved in the index stroke [cases (%)]

12 (75.00%)

4 (66.67%)

0.541

ACC involved in the recurrent stroke [cases (%)]

14 (82.35%)

5 (83.33%)

0.73

TOAST classification

   

 LAA [cases (%)]

7 (43.75%)

2 (33.33%)

0.523

 CE [cases (%)]

5 (31.25%)

3 (50.00%)

0.369

 SAO [cases (%)]

4 (25.00%)

1 (16.67%)

0.581

Baseline NIHSS of the index stroke [median (min, max)]

7.00 (2, 14)

14.50 (6, 19)

0.1

Baseline NIHSS of the recurrent stroke [median (min, max)]

10.40 (2, 22)

18.00 (8, 24)

0.056

OTT of the previous IVT (min) [median (min, max)]

106.67 (44, 240)

120.00 (35, 350)

0.953

OTT of the RIVT (min) [median (min, max)]

85.00 (33, 220)

179.50 (44, 420)

0.221

The interval between two IVT (day) [median (min, max)]

9.50 (0.25, 90)

18.00 (2, 73)

0.974

Good outcome after previous IVT [cases (%)]

18 (100.00%)

4 (66.67%)

0.054

  1. Abbreviations: ACC = anterior cerebral circulation; LAA = large artery atherosclerotic; cardiogenic embolism; SAO = small artery occlusion; OTT = onset-to-treatment time; IVT = intravenous thrombolysis.