Fig. 3

Variability in Expression Levels of IL-6, IL-8, IL-10, and TNF-α in CSF Among ICH Patients Stratified by GCS Values. (A) IL-6 concentrations in the CSF of ICH patients possessing a GCS between 3–8 were notably elevated when juxtaposed to those encompassing a GCS of 9–15 (p < 0.001). (B) IL-8 concentrations were discernibly enhanced in the CSF of ICH patients within the 3–8 GCS range compared to those in the 9–15 range (p < 0.01). (C) ICH patients with a GCS range of 3–8 displayed pronounced IL-10 levels in the CSF relative to the 9–15 GCS cohort (p < 0.01). (D) CSF TNF-α concentrations in ICH patients situated in the 3–8 GCS range exceeded those in the 9–15 GCS cohort (p < 0.05). Note: The original result values have been transformed to their square root equivalents to facilitate a more distinct and three-dimensional portrayal of data distribution, denoted in sqrt pg/ml. Data is tabulated as M (P25, P75), with *** indicating P < 0.001, ** denoting P < 0.01, and * representing P < 0.05. Both GCS cohorts, 3–8 and 9–15, consisted of n = 50