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Fig. 6 | BMC Neurology

Fig. 6

From: Association of inflammatory cytokines expression in cerebrospinal fluid with the severity and prognosis of spontaneous intracerebral hemorrhage

Fig. 6

Comparative Analysis of IL-6, IL-8, IL-10, and TNF-α CSF Expression Across ICH Patients Stratified by GOS. (A) CSF concentrations of IL-6 in subjects with GOS scores between 1 and 3 notably exceeded those with scores between 4 and 5 (p < 0.0001). (B) Similarly, IL-8 CSF concentrations for GOS scores of 1 to 3 were elevated in comparison to scores of 4 to 5 (p < 0.0001). (C) IL-10 levels in the CSF were elevated for GOS scores of 1 to 3 relative to 4 to 5 (p < 0.001). (D) TNF-α concentrations within the CSF of subjects with GOS scores of 1 to 3 markedly surpassed those scoring between 4 and 5 (p < 0.0001). Note: The original result values have been transformed to their square root equivalents to facilitate a more distinct and three-dimensional portrayal of data distribution, denoted in sqrt pg/ml. Data is systematically presented as M (P25, P75), with *** denoting P < 0.001, and **** indicating P < 0.0001. Cohorts: GOS of 1–3, n = 53; GOS of 4–5, n = 47

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BMC Neurology

ISSN: 1471-2377

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