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Table 1 Demographic and Baseline Characteristics

From: Association of inflammatory cytokines expression in cerebrospinal fluid with the severity and prognosis of spontaneous intracerebral hemorrhage

Characteristic

Control group (n = 50)

ICH group (n = 100)

P value

Sex, n (%)

  

0.389

 Female

14(28)

35(35)

 

 Male

36(72)

65(65)

 

Age, yr, mean (SD)

31.02(15.00)

58.52(13.22)

< 0.0001*

BMI(Kg/m2), median (IQR)

24.22(23.39–26.23)

24.22(23.43–26.03)

0.484

Hypertension, n (%)

12(24)

55(55)

< 0.001*

Diabetes, n (%)

4(8)

12(12)

0.454

Hematoma location, n (%)

  

N/A

 Basal ganglia

N/A

45(45)

 

 Lobar

N/A

14(14)

 

 Thalamus

N/A

26(26)

 

 Cerebellum

N/A

6(6)

 

 Brainstem

N/A

3(3)

 

 Ventricle

N/A

6(6)

 

Into the ventricle, n (%)

N/A

45(45)

N/A

Final ICH volume(ml), n (%)

  

N/A

 < 30

N/A

52(52)

 

 ≥ 30

N/A

48(48)

 

Hydrocephalus, n (%)

N/A

16(16)

N/A

GCS, median (IQR)

N/A

9(5–12)

N/A

Time from symptom onset to MIS (hours), mean (SD)

N/A

4.15(3.62)

N/A

Infection while in hospital, n (%)

N/A

27(27)

N/A

Routine examination of CSF

   

 WBC(n), median (IQR)

3(2–6)

20(6-233)

< 0.0001*

 RBC(n), median (IQR)

6(3.75-10)

3580(212.5-13100)

< 0.0001*

Biochemical reactions of CSF

   

 PRO(g/L), median (IQR)

0.245(0.190–0.310)

1.10(0.53–2.20)

< 0.0001*

 GLU (mmol/L), median (IQR)

3.315(3.133–3.603)

3.830(3.180–5.640)

< 0.001*

 CL (mmol/L), median (IQR)

121.4(120.4-122.8)

122.5(117.6-127.3)

0.471

GOS, n (%)

  

N/A

 1 ~ 3

N/A

53(53)

 

 4 ~ 5

N/A

47(47)

 
  1. Note: The primary disease or clinical reason/indication for CSF sampling in the control group was due to the patients displaying symptoms such as fever, headache, nausea, vomiting, and neck stiffness. These symptoms led clinicians to suspect the presence of a central nervous system disease
  2. Abbreviations: GCS, Glasgow coma scale; ICH, Intracerebral hemorrhage; IQR, Interquartile range; MIS, minimally invasive surgery; SD, standard deviation; BMI, Body Mass Index; CSF, Cerebrospinal fluid; WBC, White blood cell; RBC, Red blood cell; PRO, protein; GLU, glucose; GOS, Glasgow outcome scale. * Statistically significant