Table 2 Baseline characteristics of included studies populations
Study | Age | Male | AF | NIHSS | Hypertension | Diabetes | Hyperlipidemia | Smoking | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DOAC | Control | DOAC | Control | DOAC | Control | DOAC | Control | DOAC | Control | DOAC | Control | DOAC | Control | DOAC | Control | |
Kam et al. (2022) | 75 [64–82] | 70 [58–81] | 1,186 (53.7) | 81,857 (50.9) | 1614 (73.1) | 23,458 (14.6) | 10 [5–17] | 7 [4–14] | 1753 (79.4) | 115,623 (71.9) | 719 (32.6) | 46,926 (29.2) | 1,099 (49.8) | 72,112 (44.8) | 242 (11.0) | 29,045 (18.1) |
Meinel et al. (2023) | 79 [71–85] | 72 [62–80] | 477 (57.3) | 18 264 (56.4) | 608 (90.1) | 4,008 (25.1) | 11 [6–17] | 9 [5–16] | 565 (75.1) | 20,072 (62.2) | 173 (23.2) | 6,311 (19.6) | 322 (43.2) | 12,091 (37.6) | 95 (12.8) | 5,796 (19.6) |
Okada et al. (2022) | 80 [74–87] | 76 [68–84] | 29 (72.5) | 474 (62.9) | 36 (90.0) | 236 (31.3) | 15 [5–24] | 9 [4–17] | 33 (82.5) | 537 (71.3) | 8 (20.0) | 154 (20.5) | 21 (52.5) | 398 (52.9) | 11 (27.5) | 197 (26.2) |
Seiffge et al. (2015) | 76 [68–81] | 71 [60–79] | 42 (53.8) | 5,023 (56.2) | 68 (87.2) | 2,152 (24.3) | 14.5 [7–19] | 10 [6–16] | 61 (87.1) | 5,627 (63.2) | 17 (24.3) | 1,500 (16.8) | 32 (49.2) | 3,559 (41.4) | NR | NR |
Xian et al. (2017) | 74 [66–82] | 71 [59–82] | 122 (48.6) | 20,545 (49.9) | 196 (78.1) | 7,430 (18.1) | 12 [6–18] | 9 [5–15] | 198 (78.9) | 30,106 (73.2) | 64 (25.5) | 11,211 (27.3) | 106 (42.2) | 17,916 (43.6) | 19 (7.6) | 7,339 (17.8) |
Tsai et al. (2023) | 74.1 [8.9] | 67.2 [12.8] | 40 (44.0) | 4448 (61.7) | 80 (87.9) | 2230 (30.9) | 14.2 [4.7] | 13.0 [4.6] | NR | NR | NR | NR | NR | NR | NR | NR |