Table 4 Factors associated with the development of drug-resistant epilepsy
Drug-Resistant Epilepsy | ||||
|---|---|---|---|---|
Variable | Category | Yes% | No% | P value |
Sex | Male | 20(15) | 113(85) | 0.9 |
Female | 15(14.6) | 88(85.4%) | ||
Seizure types | 1 | 24(12.8) | 164(87.2) | 0.077 |
≥ 2 | 11(22.9) | 37(77.1) | ||
Number of seizures at onset. | < 10 | 12(7.7) | 144(92.3) | < 0.001 |
≥ 10 | 23(28.7) | 57(71.3) | ||
Developmental delay** | Yes | 24(20.3) | 94(79.7) | 0.017 |
No | 11(9.3) | 107(90.7) | ||
Neonatal seizures | Yes | 16(25.8) | 46(74.2) | 0.007 |
No | 19(10.9) | 155(89.1) | ||
Epilepsy syndrome | Yes | 8(21.1) | 30(78.9) | 0.23 |
No | 27(13.6) | 171(86.4) | ||
History of status epilepticus | Yes | 20(27.4) | 53(72.6) | < 0.001 |
No | 15(9.2) | 148(90.8) | ||
Consanguinity | Yes | 1(14.3) | 6(85.7) | 0.31* |
No | 34(14.8) | 195(85.2) | ||
MRI (N = 141) | Normal | 7(12.1) | 51(87.9) | 0.003 |
Abnormal | 28(33.7) | 55(66.3) | ||
EEG (N = 169) | Normal | 6(13.3) | 39(86.7) | 0.281 |
Abnormal | 29(23.3) | 95(76.7) | ||