Table 1 Baseline characteristics of the cohort (n = 3,144)
| Â | Total |
|---|---|
Age, y [IQR] | 56 [50–63] |
Sex, male, n (%) | 1,696 (53.9) |
Body mass index, kg/m2 [IQR] | 24.00 [22.11–25.93] |
Hypertension, n (%) | 791 (25.2) |
Diabetes, n (%) | 462 (14.7) |
Hyperlipidemia, n (%) | 480 (15.3) |
Ischemic heart disease, n (%) | 108 (3.4) |
Current smoking, n (%) | 565 (18.0) |
Use of antiplatelet agents, n (%) | 317 (10.1) |
Systolic blood pressure, mmHg [IQR] | 125 [115–136] |
Diastolic blood pressure, mmHg [IQR] | 75 [69–83] |
Hemoglobin A1c, % [IQR] | 5.7 [5.5–6.0] |
Fasting glucose, mmol/L [IQR] | 5.06 [4.72–5.61] |
Total cholesterol, mmol/L [IQR] | 5.12 [4.50–5.74] |
LDL cholesterol, mmol/L [IQR] | 3.23 [2.64–3.83] |
HDL cholesterol, mmol/L [IQR] | 1.37 [1.16–1.63] |
Triglyceride, mmol/L [IQR] | 1.13 [0.82–1.63] |
White blood cell counts, × 103/μL [IQR] | 5.32 [4.40–6.38] |
Neutrophil counts, × 103/μL [IQR] | 2.88 [2.22–3.68] |
Lymphocyte counts, × 103/μL [IQR] | 1.86 [1.54–2.22] |
Monocyte counts, × 103/μL [IQR] | 0.34 [0.27–0.44] |
High-sensitivity CRP, mg/dL [IQR] | 0.04 [0.01–0.15] |
Neutrophil to lymphocyte ratio, [IQR] | 1.53 [1.18–2.03] |
Monocyte to HDL cholesterol ratio, [IQR] | 0.25 [0.18–0.35] |
WMH volume, mL [IQR] | 1.04 [0.20–2.60] |
Lacunes of presumed vascular origin, n (%) | 230 (7.3) |
Cerebral microbleeds, n (%) | 129 (4.1) |