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Table 4 Multivariable logistic regression analyses to evaluate the association between possible predictors and lacune/cerebral microbleeds

From: Monocyte to high-density lipoprotein cholesterol ratio is associated with cerebral small vessel diseases

 

Lacune

Cerebral microbleeds

Adjusted OR [95% CI]

P-value

Adjusted OR [95% CI]

P-value

Age

1.09 [1.07–1.11]

 < 0.001

1.06 [1.04–1.08]

 < 0.001

Sex, male

…

…

…

…

Body mass index

…

…

…

…

Hypertension

1.32 [0.99–1.78]

0.063

1.47 [0.99–2.16]

0.054

Diabetes

1.11 [0.68–1.81]

0.671

0.99 [0.63–1.57]

0.974

Hyperlipidemia

…

…

…

…

Ischemic heart disease

…

…

…

…

Current smoking

…

…

…

…

Use of anti-PLT

…

…

1.18 [0.71–1.96]

0.531

Systolic BP

1.00 [0.99–1.02]

0.720

1.01 [1.00–1.03]

0.023

Diastolic BP

1.02 [1.00–1.05]

0.045

…

…

Hemoglobin A1c

0.60 [0.22–1.62]

0.314

…

…

Fasting glucose

4.25 [0.66–27.30]

0.128

…

…

Total cholesterol

…

…

…

…

LDL cholesterol

…

…

…

…

HDL cholesterol

…

…

…

…

Triglyceride

…

…

…

…

WBC counts

…

…

…

…

Neutrophil counts

…

…

…

…

Lymphocyte counts

…

…

…

…

Monocyte counts

…

…

…

…

High-sensitivity CRP

…

…

…

…

NLR

…

…

…

…

MHR

1.43 [1.07–1.91]

0.016

1.51 [1.03–2.19]

0.033

  1. Anti-PLT antiplatelet agent, BP blood pressure, LDL low-density lipoprotein, HDL high-density lipoprotein, WBC white blood cell, CRP C-reactive protein, NLR neutrophil to lymphocyte ratio, MHR monocyte to HDL cholesterol ratio