Efficacy and safety of hyperbaric oxygen therapy in acute ischaemic stroke: a systematic review and meta-analysis

BMC Neurology

Table 2 The modes of HBOT intervention in the 8 RCTs

Study	FiO₂	Pressure	Begin time	Treatment time	Therapy duration
Chen 2012	100%O₂	2ATA	Within 3 ~ 5days after stroke onset	60 min	qd, 10days
Chen 2018	100%O₂	2.5ATA	NR	60 min	Once
Nighoghossian 1995	100%O₂/air^#	1.5ATA/1.5ATA^#	Within 24 h after stroke onset	40 min/40min^#	a total of 10 dives
Rusyniak 2003	100%O₂/100%O₂^#	2.5ATA/1.14ATA^#	Within 24 h since symptom onset	60 min/60min^#	Once
Zhu 2022	NR	2ATA	NR	80 min	q3d, 36days
Imai 2006	100%O₂	2ATA	NR	60 min	qd, 1week
Zhao 2008	99%O₂	2ATA	Within 1 ~ 3days following admission	60 min	qd, 10days
Dong 2023	NR	2ATA	NR	60 min	qd, 12weeks^*

IG: interventional group;CG: controlled group; NR: not reported; qd: once a day; q3d: once every 3 days
^#Data are given as Treatment/Control
^*10 cycles as a treatment course, with an interval of three days between courses

ISSN: 1471-2377