Fig. 1From: Hand knob sign in osmotic demyelinating syndromedisplays magnetic resonance imaging (MRI) of the brain at the onset of symptoms, revealing symmetrical increased signal intensity on FLAIR in the bilateral lentiform and caudate nuclei (A), and hyperintensity on diffusion-weighted imaging (DWI) (B). An MRI of the brain performed three weeks after symptom onset revealed hyperintensity on FLAIR in the pons (C) and bilateral precentral gyri, including the hand knob area (D)Back to article page