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Table 3 MRI sequences and characteristics at 24 h and 12 months

From: Exploring vascular contributions to cognitive impairment and dementia (ENIGMA): protocol for a prospective observational study

Sequence

Description

Purpose

DWI + ADC

Diffusion Weighted Imaging (DWI) and calculated Apparent Diffusion Coefficient (ADC)

Grey and white matter microstructural integrity, including dendrite density, axonal density and dispersion, and intra- and extra-axonal water diffusivity

Kurtosis

Kurtosis diffusion Imaging

3D FLAIR

3-Dimensional Fluid-Attenuated Inversion Recovery

White matter hyperintensities, perivascular spaces, and lacunes

3D T1 (MP2RAGE)

3-Dimentional T1- magnetization Prepared Rapid Gradient Echo

Atrophy/cortical thickness

SWI

Susceptibility Weighted Imaging

Microbleeds and superficial siderosis

PWI GRE

Gradient Echo Perfusion Imaging

Capillary transit time heterogeneity

PWI SE

Spin Echo Perfusion Imaging