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Table 6 Daily Parkinson symptom log

From: A randomized feasibility trial of medium chain triglyceride-supplemented ketogenic diet in people with Parkinson's disease

 

Ketogenic Diet

Standard Diet

Visit

Day 1

Day 2

Day 3

Day 4

Day 5

Day 6

Day 7

Wk 3

Day 1

Day 2

Day 3

Day 4

Day 5

Day 6

Day 7

Wk 3

tremor

1

1.17

1

1

1

1

1

1

1

0.6

1

1

0.8

1.2

1

0.83

dyskinesia

1.25

1.25

1

1

0.75

1

1

0.67

1

1

1.4

1.2

0.8

0.8

1.17

0.67

off medication state

1.25

1.2

1

1

1

1

1

0.8

1.14

1

1

1

1

1.13

0.86

0.86

concentration

1

1

1

1

1.33

1

1

 

1

1

1

1

1

1

1

1

pain

0.8

0.8

1.2

1.4

1

1

1

0.67

1.17

0.67

1

0.67

1

0.71

0.83

1

urinary frequency

1

0.83

1

1

1.17

1

1.25

0.67

1

1.13

1

0.89

0.78

0.88

0.78

0.71

bradykinesia

1

1.17

1

1

0.83

0.75

1.2

1

1

1

1

1

1

0.78

1

0.67

depression

1

1

1.5

1

1

1.5

0.5

1

1.33

1

0.67

0.67

1

1

1

1

anxiety

1

1

1

1

1

1

1

0.67

1

1.2

0.8

1.33

1

1

1

1

fatigue

1

0.8

1

0.75

1.2

1.8

1

1.2

1.17

1.33

1.43

0.88

1.17

1.14

1.17

1.17

apathy

1

1

1

1.33

1

1

1

1

1

1

1

0.67

1

1

1

1

dystonia

1.6

1

1

1

0.75

1

1

0.83

1

1

1

1

1

0.8

1

1.2

% off

0.5

0.67

0.83

0.5

0.5

0.67

0.5

0.83

1.22

0.78

0.89

1.11

1.11

1.11

1.22

1.29

  1. Parkinson symptom daily inventory, administered on inpatient day 1 (regular diet), inpatient days 2–7 (randomized ketogenic diet (KD) or standard diet (SD), and final study visit (Week 3, following 2 weeks outpatient KD for both groups). Reported are mean values. Value < 1 indicates better than normal, and > 1 indicates worse than normal. Daily off time was greater in the SD group than KD group (p = 0.00005), otherwise group differences were not statistically significant.
  2. Dysk Dyskinesia, off off medication state, conc concentration, bradyk bradykinesia, depr depression, anx anxiety.
  3. •For PD symptoms: 0 is better than normal 1 is normal 2 is worse than normal.
  4. •For (daily) % off (of medication state), 0 = 0%, 1 = 1–10%, 2 = 11–25% 3 = 26–50% 4 =  > 50%