Table 1 The clinical characteristics of the study samples

Age(years), mean(SD)

53.09(1.75)

47.79(1.17)

0.011

Male, n(%)

26(51)

49(48)

0.732

Alcohol consumption, n(%)

4(8)

13(13)

0.363

Current smoking, n(%)

15(29)

61(40)

0.192

Coronary artery disease, n(%)

3(6)

10(10)

0.546

Atrial fibrillation, n(%)

3(6)

8(8)

0.753

Hypertension, n(%)

13(26)

21(21)

0.492

Diabetes mellitus, n(%)

13(26)

22(22)

0.586

BMI, median (IQR)

23.26(21.16,26.26)

24.27(22.02,26.56)

0.392

Aura migraine, n(%)

21(41)

34(33)

0.341

Migraine years, median (IQR)

5(3,7)

5(3,7)

0.704

WBC(10⁹/Ul), median (IQR)

6.90(5.70,8.80)

6.70(5.50,8.20)

0.404

HGB (10 ⁹ /L), mean (SD)

142.51(13.10)

140.96(12.26)

0.517

RBC(10 ⁹ /L), median (IQR)

4.89(4.59,5.12)

4.64(4.35,4.97)

0.011

RDW (%),median (IQR)

12.77(12.30,13.75)

12.70(12.07,13.40)

0.178

PLT(10 ⁹ /L), mean (SD)

233.37(73.26)

225.20(53.14)

0.077

PDW, median (IQR)

12.90(11.30,15.70)

12.45(10.98,15.50)

0.383

MPV, median (IQR)

10.30(9.60,11.40)

10.00(9.40,10.53)

0.023

CRP (mg/L) median (IQR)

4.80(1.50,7.35)

2.35(0.90,4.20)

0.005

FIB(g/L), median (IQR)

2.70(2.23,2.98)

2.32(2.04,2.78)

0.006

UA(µmol/L), median (IQR)

342(272,387)

350(292,420)

0.318

TG(mmol/L), median (IQR)

1.16(0.86,1.93)

1.24(0.91,1.63)

0.745

TC(mmol/L), median (IQR)

4.59(3.73,5.17)

4.87(4.34,5.64)

0.003

LDL(mmol/L), median (IQR)

2.66(2.17,3.18)

2.74(2.37,3.14)

0.438

HDL(mmol/L), median (IQR)

1.26(1.04,1.47)

1.33(1.08,1.50)

0.406

CGRP(pg/mL), median (IQR)

83(78,88)

64(52,68)

< 0.001

HIT-6,median (IQR)

66(58,72)

60(52,68)

0.002

Medication history

Antihypertensive therapy, n(%)

28(55)

53(52)

0.731

Antiglycemic therapy, n(%)

17(33)

36(35)

0.810

Anticoagulant therapy, n(%)

1(2)

3(3)

1.000

Oral painkillers, n(%)

46(90)

98(96)

0.161