Table 3 The clinical characteristics of the study samples

Age(years), mean(SD)

50.50(11.20)

55.13(14.08)

52.15(10.93)

0.313

0.953

0.339

Male, n(%)

7(50)

13(54)

6(0.46)

0.804

0.842

0.642

Alcohol consumption, n(%)

1(7.14)

2(8.33)

1(7.69)

0.896

0.957

0.210

Current smoking, n(%)

3(21.43)

9(37.50)

3(23.08)

0.304

0.918

0.371

CAD, n(%)

2(14.29)

0(0)

1(7.69)

0.057

0.586

0.168

AF, n(%)

2(14.29)

1(4.17)

0(0)

0.246

0.157

0.456

Hypertension, n(%)

3(21.43)

8(33.33)

2(15.38)

0.435

0.686

0.241

Diabetes mellitus, n(%)

3(21.43)

6(25)

4(30.77)

0.803

0.580

0.706

BMI, mean (SD)

23.81(3.37)

25.28(4.50)

22.35(2.52)

0.179

0.344

0.029

MA nMA, n(%)

5(35.17)

13(54.17)

3(23.08)

0.183

0.472

0.068

MA years, median (IQR)

5(2,8.25)

4(3,6.75)

6(4,7.5)

0.879

0.365

0.017

ASA, n(%)

1(7.14)

3(12.5)

1(7.69)

0.604

0.954

0.653

PFO diameter, median(IQR)

1.97(1.85,2.18)

2.20(2.07,2.38)

2.28(2.06,2.65)

0.017

0.014

0.004

PFO length, mean(SD)

12.22(2.45)

12.78(3.01)

12.87(2.50)

0.608

0.541

0.311

WBC(10⁹/Ul), median(IQR)

6.91(5.68,8.93)

6.80(5.34,9.00)

6.90(5.74,8.55)

0.928

0.364

0.975

HGB (10 ⁹ /L), mean (SD)

144.58(11.51)

144.00(12.30)

137.54(15.68)

0.822

0.533

0.111

RBC(10 ⁹ /L), median(IQR)

4.98(4.65,5.31)

4.85(4.62,5,01)

4.62(4.34,5.15)

0.397

0.225

0.399

RDW (%),median (IQR)

12.69(0.94)

12.33(11.56,12.80)

12.25(11.73,12.70)

0.244

0.253

0.899

PLT(10 ⁹ /L), mean (SD)

206.64(69.78)

242(82.85)

246(52.66)

0.494

0.436

0.714

PDW, median(IQR)

11.65(10.60,14.25)

15.05(11.78,16.08)

13.10(11.85,15.00)

0.023

0.126

0.474

MPV, median(IQR)

10.45(9.33,11.83)

10.30(9.53,11.70)

10.10(9.70,10.75)

0.774

0.662

0.483

CRP (mg/L), median(IQR)

6.34(1.48,7.62)

4.29(1.28,7.19)

4.20(1.55,6.33)

0.496

0.497

0.861

FIB(g/L), median(IQR)

2.68(2.22,3.08)

2.78(2.18,2.98)

2.63(2.20,2.74)

0.774

0.771

0.545

UA(µmol/L), median(IQR)

333(261,373)

347(286,480)

307(263,383)

0.238

0.865

0.186

TG(mmol/L), median(IQR)

1.31(0.71,2.40)

1.16(0.99,1.91)

1.02(0.72,1.79)

0.342

0.645

0.324

TC(mmol/L), mean (SD)

4.42(0.78)

4.41(0.94)

4.58(1.19)

0.881

0.376

0.417

LDL(mmol/L), mean (SD)

2.68(0.62)

2.62(0.89)

2.69(0.87)

0.358

0.428

0.611

HDL(mmol/L), mean (SD)

1.24(0.31)

1.26(0.33)

1.37(0.32)

0.927

0.895

0.399

CGRP(pg/mL), median(IQR)

78(73,81)

83(79,87)

91(87,92)

0.006

0.001

0.003

HIT-6 ,mean (SD)

65.57(10.99)

67.88(7.41)

62.00(10.00)

0.229

0.877

0.081